Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ELOVL6
  • Mouse genes Elovl6
  • Rat genes Elovl6
  • Zfish genes elovl6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Elovl6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	Elovl6	IDA		Mouse	PMID:11567032
Molecular Function	GO:0009922	fatty acid elongase activity	ELOVL6	IMP		Human	PMID:25003994
Molecular Function	GO:0009922	fatty acid elongase activity	ELOVL6	IGI	UniProtKB:Q9VV87	Human	PMID:26214738
Molecular Function	GO:0009922	fatty acid elongase activity	Elovl6	IDA		Rat	PMID:12005057|RGD:8554529
Molecular Function	GO:0005515	protein binding	ELOVL6	IPI	UniProtKB:Q96G23	Human	PMID:20937905
Molecular Function	GO:0005515	protein binding	ELOVL6	IPI	UniProtKB:P09601	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ELOVL6	IPI	UniProtKB:Q13094	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ELOVL6	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	ELOVL6	IDA		Human	PMID:20937905
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Elovl6	IDA		Mouse	PMID:11567032
Cellular Component	GO:0009923	fatty acid elongase complex	ELOVL6	IDA		Human	PMID:25003994
Biological Process	GO:0030497	fatty acid elongation	Elovl6	IDA		Mouse	PMID:11567032
Biological Process	GO:0030497	fatty acid elongation	elovl6	IMP	ZFIN:ZDB-GENO-220428-14	Zfish	PMID:32325903
Biological Process	GO:0034625	fatty acid elongation, monounsaturated fatty acid	Elovl6	IDA		Rat	PMID:12005057|RGD:8554529
Biological Process	GO:0019367	fatty acid elongation, saturated fatty acid	ELOVL6	IDA		Human	PMID:20937905
Biological Process	GO:0019367	fatty acid elongation, saturated fatty acid	ELOVL6	IGI	UniProtKB:Q9VV87	Human	PMID:26214738
Biological Process	GO:0019367	fatty acid elongation, saturated fatty acid	Elovl6	IDA		Rat	PMID:12005057|RGD:8554529
Biological Process	GO:0042759	long-chain fatty acid biosynthetic process	ELOVL6	IDA		Human	PMID:20937905
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Elovl6	IMP		Mouse	MGI:MGI:6101069|PMID:26628376

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern