Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EMC8
  • Mouse genes Emc8
  • Rat genes Emc8
  • Zfish genes emc8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Emc8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032977	membrane insertase activity	EMC8	IMP		Human	PMID:29809151
Molecular Function	GO:0032977	membrane insertase activity	EMC8	IMP		Human	PMID:30415835
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EMC8	IPI	UniProtKB:Q15006	Human	PMID:32439656
Cellular Component	GO:0005737	cytoplasm	EMC8	IDA		Human	PMID:22119785
Cellular Component	GO:0072546	EMC complex	EMC8	IPI		Human	PMID:32439656
Cellular Component	GO:0072546	EMC complex	EMC8	IDA		Human	PMID:22119785
Cellular Component	GO:0005783	endoplasmic reticulum	EMC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	EMC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	EMC8	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Emc8	HDA		Mouse	PMID:14651853
Biological Process	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	EMC8	IDA		Human	PMID:29242231
Biological Process	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	EMC8	IMP		Human	PMID:29809151
Biological Process	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	EMC8	IMP		Human	PMID:30415835
Biological Process	GO:0071816	tail-anchored membrane protein insertion into ER membrane	EMC8	IDA		Human	PMID:29242231

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern