Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EMILIN1
  • Mouse genes Emilin1
  • Rat genes Emilin1
  • Zfish genes emilin1a,emilin1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Emilin1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030023	extracellular matrix constituent conferring elasticity	Emilin1	IMP	MGI:MGI:3028845	Mouse	PMID:14701737
Molecular Function	GO:0042802	identical protein binding	EMILIN1	IPI	UniProtKB:Q9Y6C2	Human	PMID:10821830
Molecular Function	GO:0042802	identical protein binding	EMILIN1	IPI	UniProtKB:Q9Y6C2	Human	PMID:18463100
Molecular Function	GO:0042802	identical protein binding	EMILIN1	IPI	UniProtKB:Q9Y6C2	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	Emilin1	IDA		Mouse	PMID:14701737
Molecular Function	GO:0098640	integrin binding involved in cell-matrix adhesion	EMILIN1	IMP		Human	PMID:18463100
Molecular Function	GO:0060090	molecular adaptor activity	EMILIN1	IMP		Human	PMID:18463100
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q9BXX0	Human	PMID:11278945
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q13287	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96QG7	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96QG7	Human	PMID:19447967
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96QG7	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q00994	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q13287	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q53FD0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q5H9J7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q5JTB6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q6ISS4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q86VP1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q8IY31	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q8N443	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96PC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96QG7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q2FZB8	Human	PMID:26627825
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96QG7	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q5H9J7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EMILIN1	IPI	UniProtKB:Q96QG7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Emilin1	IPI	UniProtKB:Q9WVJ9	Mouse	MGI:MGI:6478060|PMID:28717224
Molecular Function	GO:0005515	protein binding	Emilin1	IPI	UniProtKB:P07200	Mouse	MGI:MGI:3692357|PMID:16530041
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:23979707
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	IMP		Human	PMID:26462740
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EMILIN1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Emilin1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Emilin1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Emilin1	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:1990971	EMILIN complex	EMILIN1	IPI		Human	PMID:10821830
Cellular Component	GO:1990971	EMILIN complex	EMILIN1	IMP		Human	PMID:18463100
Cellular Component	GO:0070062	extracellular exosome	EMILIN1	HDA		Human	PMID:21362503
Cellular Component	GO:0031012	extracellular matrix	Emilin1	IDA		Mouse	PMID:14701737
Cellular Component	GO:0005615	extracellular space	EMILIN1	IMP		Human	PMID:26462740
Cellular Component	GO:0005615	extracellular space	Emilin1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0034668	integrin alpha4-beta1 complex	EMILIN1	IMP		Human	PMID:18463100
Biological Process	GO:0003180	aortic valve morphogenesis	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0140060	axon arborization	emilin1a	IMP	ZFIN:ZDB-MRPHLNO-110607-8	Zfish	PMID:31978608
Biological Process	GO:0033627	cell adhesion mediated by integrin	Emilin1	IDA		Mouse	MGI:MGI:5295900|PMID:21949412
Biological Process	GO:0016477	cell migration	EMILIN1	IMP		Human	PMID:18463100
Biological Process	GO:0007160	cell-matrix adhesion	EMILIN1	IMP		Human	PMID:18463100
Biological Process	GO:0048251	elastic fiber assembly	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0030198	extracellular matrix organization	Emilin1	IDA		Mouse	PMID:18757743
Biological Process	GO:0030097	hemopoiesis	emilin1a	IMP	ZFIN:ZDB-MRPHLNO-110607-8	Zfish	PMID:21571218
Biological Process	GO:0016525	negative regulation of angiogenesis	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0050866	negative regulation of cell activation	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:1904027	negative regulation of collagen fibril organization	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0010629	negative regulation of gene expression	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:1905522	negative regulation of macrophage migration	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0045766	positive regulation of angiogenesis	Emilin1	IDA		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Emilin1	IDA		Mouse	PMID:18757743
Biological Process	GO:1900426	positive regulation of defense response to bacterium	EMILIN1	IDA		Human	PMID:17988845
Biological Process	GO:1901203	positive regulation of extracellular matrix assembly	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0010628	positive regulation of gene expression	Emilin1	IMP		Mouse	MGI:MGI:5605894|PMID:25056700
Biological Process	GO:0008217	regulation of blood pressure	Emilin1	IDA		Mouse	MGI:MGI:5514200|PMID:22814752
Biological Process	GO:0042127	regulation of cell population proliferation	Emilin1	IMP		Mouse	MGI:MGI:5295900|PMID:21949412

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern