Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EML4
  • Mouse genes Eml4
  • Rat genes Eml4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eml4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	EML4	IDA		Human	PMID:31409757
Molecular Function	GO:0048487	beta-tubulin binding	EML4	IDA		Human	PMID:31409757
Molecular Function	GO:0005515	protein binding	EML4	IPI	UniProtKB:Q9Y266	Human	PMID:25789526
Molecular Function	GO:0043621	protein self-association	EML4	IDA		Human	PMID:25740311
Cellular Component	GO:0005737	cytoplasm	EML4	IDA		Human	PMID:16890222
Cellular Component	GO:0005829	cytosol	EML4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	EML4	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	EML4	IDA		Human	PMID:16890222
Cellular Component	GO:0005874	microtubule	EML4	IDA		Human	PMID:31409757
Cellular Component	GO:0015630	microtubule cytoskeleton	EML4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	Eml4	IDA		Mouse	PMID:17196341
Cellular Component	GO:0005815	microtubule organizing center	EML4	IDA		Human	PMID:16890222
Cellular Component	GO:0005815	microtubule organizing center	EML4	IDA		Human	PMID:25789526
Cellular Component	GO:0030496	midbody	EML4	IDA		Human	PMID:25789526
Cellular Component	GO:0072686	mitotic spindle	EML4	IDA		Human	PMID:16890222
Cellular Component	GO:0072686	mitotic spindle	EML4	IDA		Human	PMID:25789526
Cellular Component	GO:0072686	mitotic spindle	Eml4	IDA		Mouse	PMID:17196341
Biological Process	GO:0008608	attachment of spindle microtubules to kinetochore	EML4	IMP		Human	PMID:25789526
Biological Process	GO:0007080	mitotic metaphase plate congression	EML4	IMP		Human	PMID:25789526
Biological Process	GO:0007026	negative regulation of microtubule depolymerization	Eml4	IMP		Mouse	PMID:17196341

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern