Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ENAH
  • Mouse genes Enah
  • Rat genes Enah
  • Zfish genes enah
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Enah

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005522	profilin binding	Enah	IDA		Mouse	MGI:MGI:1331576|PMID:10069337
Molecular Function	GO:0005515	protein binding	ENAH	IPI	UniProtKB:Q14517	Human	PMID:16979624
Molecular Function	GO:0005515	protein binding	ENAH	IPI	UniProtKB:Q9NYB0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ENAH	IPI	UniProtKB:Q9UGI8	Human	PMID:21278383
Molecular Function	GO:0005515	protein binding	Enah	IPI	UniProtKB:Q9UQB8	Mouse	MGI:MGI:5486572|PMID:11696321
Molecular Function	GO:0005515	protein binding	Enah	IPI	UniProtKB:Q6XZF7-1	Mouse	MGI:MGI:5925889|PMID:24332715
Molecular Function	GO:0005515	protein binding	Enah	IPI	PR:P05480	Mouse	PMID:8861907
Molecular Function	GO:0005515	protein binding	Enah	IPI	PR:Q8CBW3	Mouse	PMID:12672821
Molecular Function	GO:0005515	protein binding	Enah	IPI	MGI:MGI:109168	Mouse	PMID:15148305
Molecular Function	GO:0005515	protein binding	Enah	IPI	PR:Q9QXJ1	Mouse	PMID:9407065
Molecular Function	GO:0005515	protein binding	Enah	IPI	PR:P00520	Mouse	PMID:8861907
Molecular Function	GO:0005515	protein binding	Enah	IPI	RGD:1566346	Rat	PMID:21278383|RGD:7247437
Molecular Function	GO:0017124	SH3 domain binding	Enah	IDA		Mouse	PMID:9126384
Molecular Function	GO:0050699	WW domain binding	ENAH	IPI	UniProtKB:O00213	Human	PMID:17686488
Cellular Component	GO:0030054	cell junction	ENAH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ENAH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030175	filopodium	Enah	IDA		Mouse	PMID:10069337
Cellular Component	GO:0030175	filopodium	Enah	IDA		Mouse	PMID:15148305
Cellular Component	GO:0005925	focal adhesion	ENAH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	ENAH	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Enah	IDA		Mouse	MGI:MGI:1099567|PMID:8861907
Cellular Component	GO:0030027	lamellipodium	Enah	IDA		Mouse	PMID:15148305
Cellular Component	GO:0030027	lamellipodium	Enah	IDA		Mouse	PMID:12672821
Cellular Component	GO:0043005	neuron projection	Enah	IDA		Mouse	PMID:10069337
Cellular Component	GO:0005886	plasma membrane	ENAH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0001725	stress fiber	Enah	IDA		Mouse	PMID:8861907
Biological Process	GO:0030036	actin cytoskeleton organization	Enah	IGI	MGI:MGI:109268	Mouse	PMID:15371503
Biological Process	GO:0007015	actin filament organization	Enah	IDA		Mouse	MGI:MGI:1099567|PMID:8861907
Biological Process	GO:0008154	actin polymerization or depolymerization	Enah	IDA		Mouse	PMID:8861907
Biological Process	GO:0070358	actin polymerization-dependent cell motility	Enah	IDA		Mouse	MGI:MGI:1099567|PMID:8861907
Biological Process	GO:0007411	axon guidance	Enah	IMP	MGI:MGI:3056050	Mouse	PMID:10069337
Biological Process	GO:0007411	axon guidance	Enah	IGI	MGI:MGI:109268	Mouse	PMID:15371503
Biological Process	GO:0007411	axon guidance	Enah	IMP	MGI:MGI:3056050	Mouse	PMID:15371503
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Enah	IEP		Mouse	PMID:20439489
Biological Process	GO:0001843	neural tube closure	Enah	IGI	MGI:MGI:109268	Mouse	PMID:15371503
Biological Process	GO:0001843	neural tube closure	Enah	IGI	MGI:MGI:97549	Mouse	PMID:10069337

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern