Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Eng

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ENG
- Mouse genes Eng
- Rat genes Eng
- Zfish genes eng
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eng

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0036122	BMP binding	ENG	IPI	UniProtKB:P18075	Human	PMID:9872992
Molecular Function	GO:0015026	coreceptor activity	ENG	IPI	UniProtKB:P36897	Human	PMID:12015308
Molecular Function	GO:0005534	galactose binding	ENG	IDA		Human	PMID:3262645
Molecular Function	GO:0005539	glycosaminoglycan binding	ENG	IDA		Human	PMID:3262645
Molecular Function	GO:0042802	identical protein binding	ENG	IPI	UniProtKB:P17813	Human	PMID:28564608
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P36897	Human	PMID:15702480
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P37023	Human	PMID:15702480
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P37173	Human	PMID:15702480
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P01137	Human	PMID:20856203
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P05556	Human	PMID:22940691
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P08648	Human	PMID:22940691
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P02750	Human	PMID:23868260
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:Q9UK05:PRO_0000033903	Human	PMID:28564608
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P17931	Human	PMID:31540324
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P19474	Human	PMID:31540324
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P07200	Human	PMID:9872992
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P18075	Human	PMID:9872992
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:P27037	Human	PMID:9872992
Molecular Function	GO:0005515	protein binding	ENG	IPI	UniProtKB:Q13705	Human	PMID:9872992
Molecular Function	GO:0005515	protein binding	Eng	IPI	MGI:MGI:1924155	Mouse	PMID:23868260
Molecular Function	GO:0042803	protein homodimerization activity	Eng	IPI	UniProtKB:Q63961	Mouse	MGI:MGI:66318\|PMID:8194490
Molecular Function	GO:0050431	transforming growth factor beta binding	ENG	IPI	UniProtKB:P07200	Human	PMID:9872992
Molecular Function	GO:0050431	transforming growth factor beta binding	ENG	IPI	UniProtKB:P10600	Human	PMID:9872992
Molecular Function	GO:0050431	transforming growth factor beta binding	ENG	IPI	UniProtKB:P01137	Human	PMID:1326540
Molecular Function	GO:0050431	transforming growth factor beta binding	ENG	IPI	UniProtKB:P10600	Human	PMID:1326540
Molecular Function	GO:0050431	transforming growth factor beta binding	Eng	IDA		Mouse	MGI:MGI:66318\|PMID:8194490
Molecular Function	GO:0034713	type I transforming growth factor beta receptor binding	ENG	IPI	UniProtKB:P36897	Human	PMID:12015308
Molecular Function	GO:0005114	type II transforming growth factor beta receptor binding	ENG	IPI	UniProtKB:P37173	Human	PMID:12015308
Molecular Function	GO:0005114	type II transforming growth factor beta receptor binding	Eng	IPI	RGD:69651	Rat	PMID:21146604\|RGD:7257529
Cellular Component	GO:0009986	cell surface	Eng	IDA		Rat	PMID:15537649\|RGD:1601031
Cellular Component	GO:0072563	endothelial microparticle	Eng	IDA		Mouse	MGI:MGI:4850200\|PMID:20978343
Cellular Component	GO:0009897	external side of plasma membrane	ENG	IDA		Human	PMID:1537377
Cellular Component	GO:0005615	extracellular space	ENG	IDA		Human	PMID:19004009
Cellular Component	GO:0005615	extracellular space	Eng	IDA		Rat	PMID:19075097\|RGD:2313616
Cellular Component	GO:0005925	focal adhesion	ENG	HDA		Human	PMID:21423176
Cellular Component	GO:0016604	nuclear body	ENG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ENG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043235	receptor complex	ENG	IPI	UniProtKB:P27037	Human	PMID:9872992
Cellular Component	GO:0043235	receptor complex	ENG	IPI	UniProtKB:Q13705	Human	PMID:9872992
Biological Process	GO:0001525	angiogenesis	Eng	IMP	MGI:MGI:2177823	Mouse	PMID:12941632
Biological Process	GO:0001525	angiogenesis	Eng	IMP	MGI:MGI:2177822	Mouse	PMID:10625534
Biological Process	GO:0048844	artery morphogenesis	Eng	IMP		Mouse	MGI:MGI:1337912\|PMID:10348742
Biological Process	GO:0055009	atrial cardiac muscle tissue morphogenesis	Eng	IMP		Mouse	MGI:MGI:3721185\|PMID:17628518
Biological Process	GO:1905222	atrioventricular canal morphogenesis	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0048514	blood vessel morphogenesis	eng	IMP		Zfish	PMID:28530658\|ZFIN:ZDB-PUB-170523-5
Biological Process	GO:0060348	bone development	Eng	IEP		Rat	PMID:20865666\|RGD:7257537
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Eng	IMP		Mouse	MGI:MGI:1337912\|PMID:10348742
Biological Process	GO:0003209	cardiac atrium morphogenesis	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0003208	cardiac ventricle morphogenesis	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0003273	cell migration involved in endocardial cushion formation	Eng	IMP	MGI:MGI:2177824	Mouse	PMID:19703439
Biological Process	GO:0071260	cellular response to mechanical stimulus	Eng	IEP		Rat	PMID:22941949\|RGD:7248789
Biological Process	GO:0071260	cellular response to mechanical stimulus	eng	IMP		Zfish	PMID:28530658\|ZFIN:ZDB-PUB-170523-5
Biological Process	GO:0022009	central nervous system vasculogenesis	ENG	IMP		Human	PMID:7894484
Biological Process	GO:0035912	dorsal aorta morphogenesis	Eng	IMP		Mouse	MGI:MGI:2674189\|PMID:12941632
Biological Process	GO:0003203	endocardial cushion morphogenesis	Eng	IMP		Mouse	MGI:MGI:2674189\|PMID:12941632
Biological Process	GO:0003203	endocardial cushion morphogenesis	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0001886	endothelial cell morphogenesis	eng	IMP		Zfish	PMID:28530658\|ZFIN:ZDB-PUB-170523-5
Biological Process	GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0070278	extracellular matrix constituent secretion	Eng	IMP		Rat	PMID:15539634\|RGD:1601032
Biological Process	GO:0007507	heart development	Eng	IMP	MGI:MGI:2177822	Mouse	PMID:10625534
Biological Process	GO:0007507	heart development	Eng	IMP	MGI:MGI:2177824	Mouse	PMID:10562296
Biological Process	GO:0001947	heart looping	Eng	IMP		Mouse	MGI:MGI:1337912\|PMID:10348742
Biological Process	GO:0001947	heart looping	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0030336	negative regulation of cell migration	ENG	IDA		Human	PMID:19736306
Biological Process	GO:0010629	negative regulation of gene expression	Eng	IMP		Mouse	MGI:MGI:2674189\|PMID:12941632
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	ENG	IDA		Human	PMID:12015308
Biological Process	GO:0003148	outflow tract septum morphogenesis	Eng	IGI	UniProtKB:P97471	Mouse	MGI:MGI:3721185\|PMID:17628518
Biological Process	GO:0045766	positive regulation of angiogenesis	Eng	IGI	MGI:MGI:1924155	Mouse	PMID:23868260
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	ENG	IDA		Human	PMID:17068149
Biological Process	GO:0032967	positive regulation of collagen biosynthetic process	Eng	IMP		Rat	PMID:20156938\|RGD:7257540
Biological Process	GO:1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0010628	positive regulation of gene expression	Eng	IMP		Rat	PMID:21146604\|RGD:7257529
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	ENG	IDA		Human	PMID:12015308
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ENG	IGI	RNAcentral:URS00005A8080_9606	Human	PMID:26857067
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ENG	IDA		Human	PMID:12015308
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Eng	IMP		Rat	PMID:21146604\|RGD:7257529
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Eng	IMP	UniProtKB:Q02085	Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439
Biological Process	GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	Eng	IMP		Mouse	MGI:MGI:3721185\|PMID:17628518
Biological Process	GO:0006355	regulation of DNA-templated transcription	ENG	IMP		Human	PMID:15702480
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	ENG	IDA		Human	PMID:15702480
Biological Process	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	Eng	IDA		Rat	PMID:17376778\|RGD:2313627
Biological Process	GO:0031960	response to corticosteroid	Eng	IEP		Rat	PMID:19481784\|RGD:2313615
Biological Process	GO:0071559	response to transforming growth factor beta	Eng	IEP		Rat	PMID:22941949\|RGD:7248789
Biological Process	GO:0009410	response to xenobiotic stimulus	Eng	IEP		Rat	PMID:20156938\|RGD:7257540
Biological Process	GO:0048745	smooth muscle tissue development	Eng	IMP		Mouse	MGI:MGI:1337912\|PMID:10348742
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ENG	IDA		Human	PMID:12015308
Biological Process	GO:0097084	vascular associated smooth muscle cell development	Eng	IMP		Mouse	MGI:MGI:3721185\|PMID:17628518
Biological Process	GO:0001570	vasculogenesis	ENG	IMP		Human	PMID:7894484
Biological Process	GO:0001570	vasculogenesis	Eng	IMP		Mouse	MGI:MGI:1337912\|PMID:10348742
Biological Process	GO:0001570	vasculogenesis	Eng	IMP	MGI:MGI:2177824	Mouse	PMID:10562296
Biological Process	GO:0048845	venous blood vessel morphogenesis	Eng	IMP		Mouse	MGI:MGI:1337912\|PMID:10348742
Biological Process	GO:0003222	ventricular trabecula myocardium morphogenesis	Eng	IMP		Mouse	MGI:MGI:4368063\|PMID:19703439

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.