Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ENPP6
  • Mouse genes Enpp6
  • Rat genes Enpp6
  • Zfish genes enpp6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Enpp6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047390	glycerophosphocholine cholinephosphodiesterase activity	ENPP6	EXP		Human	PMID:15788404
Molecular Function	GO:0047390	glycerophosphocholine cholinephosphodiesterase activity	ENPP6	IDA		Human	PMID:15788404
Molecular Function	GO:0047390	glycerophosphocholine cholinephosphodiesterase activity	Enpp6	IMP		Mouse	MGI:MGI:6217381|PMID:26888014
Molecular Function	GO:0008889	glycerophosphodiester phosphodiesterase activity	Enpp6	IDA		Mouse	PMID:15788404
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	ENPP6	IDA		Human	PMID:15788404
Molecular Function	GO:0005515	protein binding	ENPP6	IPI	UniProtKB:Q12797-6	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	ENPP6	HDA		Human	PMID:19056867
Cellular Component	GO:0005576	extracellular region	ENPP6	IDA		Human	PMID:15788404
Cellular Component	GO:0005886	plasma membrane	ENPP6	IDA		Human	PMID:15788404
Cellular Component	GO:0005886	plasma membrane	Enpp6	IDA		Mouse	PMID:15788404
Biological Process	GO:0019695	choline metabolic process	ENPP6	IDA		Human	PMID:15788404
Biological Process	GO:0019695	choline metabolic process	Enpp6	IMP		Mouse	MGI:MGI:6217381|PMID:26888014
Biological Process	GO:0019695	choline metabolic process	Enpp6	IDA		Mouse	PMID:15788404
Biological Process	GO:0006629	lipid metabolic process	ENPP6	IDA		Human	PMID:15788404

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern