Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ENPP7
  • Mouse genes Enpp7
  • Rat genes Enpp7
  • Zfish genes enpp7.1,enpp7.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Enpp7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	ENPP7	IDA		Human	PMID:16255717
Molecular Function	GO:0008081	phosphoric diester hydrolase activity	Enpp7	IDA		Rat	PMID:16255717|RGD:25671389
Molecular Function	GO:0005515	protein binding	ENPP7	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ENPP7	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ENPP7	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ENPP7	IPI	UniProtKB:Q5JTD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ENPP7	IPI	UniProtKB:Q9BYV9	Human	PMID:32296183
Molecular Function	GO:0004767	sphingomyelin phosphodiesterase activity	ENPP7	IDA		Human	PMID:12671034
Molecular Function	GO:0004767	sphingomyelin phosphodiesterase activity	ENPP7	IDA		Human	PMID:12885774
Molecular Function	GO:0004767	sphingomyelin phosphodiesterase activity	ENPP7	IDA		Human	PMID:16255717
Molecular Function	GO:0004767	sphingomyelin phosphodiesterase activity	ENPP7	IDA		Human	PMID:28292932
Molecular Function	GO:0004767	sphingomyelin phosphodiesterase activity	Enpp7	IMP		Mouse	MGI:MGI:4947032|PMID:21177474
Molecular Function	GO:0004767	sphingomyelin phosphodiesterase activity	Enpp7	IDA		Rat	PMID:16255717|RGD:25671389
Molecular Function	GO:0008270	zinc ion binding	ENPP7	IDA		Human	PMID:28292932
Cellular Component	GO:0005794	Golgi apparatus	ENPP7	IDA		Human	PMID:12671034
Cellular Component	GO:0005902	microvillus	ENPP7	IDA		Human	PMID:12671034
Cellular Component	GO:0005886	plasma membrane	ENPP7	IDA		Human	PMID:15205117
Biological Process	GO:0055089	fatty acid homeostasis	Enpp7	IMP		Mouse	MGI:MGI:4947032|PMID:21177474
Biological Process	GO:0044241	lipid digestion	Enpp7	IMP		Mouse	MGI:MGI:4947032|PMID:21177474
Biological Process	GO:0008285	negative regulation of cell population proliferation	ENPP7	IDA		Human	PMID:12671034
Biological Process	GO:0008156	negative regulation of DNA replication	ENPP7	IDA		Human	PMID:12671034
Biological Process	GO:2000304	positive regulation of ceramide biosynthetic process	Enpp7	IMP		Mouse	MGI:MGI:4947032|PMID:21177474
Biological Process	GO:0045797	positive regulation of intestinal cholesterol absorption	Enpp7	IMP		Mouse	MGI:MGI:5574251|PMID:24650549
Biological Process	GO:2000755	positive regulation of sphingomyelin catabolic process	Enpp7	IMP		Mouse	MGI:MGI:4947032|PMID:21177474
Biological Process	GO:1904729	regulation of intestinal lipid absorption	Enpp7	IMP		Mouse	MGI:MGI:4947032|PMID:21177474
Biological Process	GO:0006684	sphingomyelin metabolic process	ENPP7	IDA		Human	PMID:12671034
Biological Process	GO:0006684	sphingomyelin metabolic process	ENPP7	IDA		Human	PMID:12885774
Biological Process	GO:0006684	sphingomyelin metabolic process	ENPP7	IDA		Human	PMID:28292932

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern