Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPB41
  • Mouse genes Epb41
  • Rat genes Epb41
  • Zfish genes epb41a,epb41b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epb41

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	EPB41	IDA		Human	PMID:16669616
Molecular Function	GO:0003779	actin binding	Epb41	IDA		Rat	PMID:11274145|RGD:11252102
Molecular Function	GO:0005516	calmodulin binding	epb41b	IDA		Zfish	PMID:17569566
Molecular Function	GO:0051219	phosphoprotein binding	EPB41	IMP		Human	PMID:20109190
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:P0DP23	Human	PMID:10692436
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:P0DP24	Human	PMID:10692436
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:P0DP25	Human	PMID:10692436
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:Q9HC77	Human	PMID:11003675
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:P11277	Human	PMID:16060676
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:Q9UBN4	Human	PMID:16254212
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:P02730	Human	PMID:16669616
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:P04921	Human	PMID:16669616
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:Q14980	Human	PMID:20109190
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:Q14980	Human	PMID:23870127
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:Q14980	Human	PMID:24996901
Molecular Function	GO:0005515	protein binding	EPB41	IPI	UniProtKB:Q12959	Human	PMID:8922391
Molecular Function	GO:0005515	protein binding	Epb41	IPI	UniProtKB:G5E829	Mouse	MGI:MGI:5496297|PMID:23460639
Molecular Function	GO:0005515	protein binding	Epb41	IPI	PR:Q9QUQ5	Mouse	PMID:18987665
Molecular Function	GO:0005515	protein binding	Epb41	IPI	RGD:621714	Rat	PMID:11274145|RGD:11252102
Molecular Function	GO:0005515	protein binding	Epb41	IPI	RGD:70902	Rat	PMID:9292722|RGD:727622
Molecular Function	GO:0005515	protein binding	epb41b	IPI	ZFIN:ZDB-GENE-010525-1	Zfish	PMID:17569566
Molecular Function	GO:0005515	protein binding	epb41b	IPI	ZFIN:ZDB-GENE-030131-7930	Zfish	PMID:17569566
Molecular Function	GO:0030507	spectrin binding	Epb41	IDA		Rat	PMID:23704327|RGD:8553853
Molecular Function	GO:0005200	structural constituent of cytoskeleton	EPB41	IMP		Human	PMID:6894932
Cellular Component	GO:0016323	basolateral plasma membrane	Epb41	IDA		Mouse	MGI:MGI:5496297|PMID:23460639
Cellular Component	GO:0005938	cell cortex	EPB41	IDA		Human	PMID:23870127
Cellular Component	GO:0030054	cell junction	EPB41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030863	cortical cytoskeleton	EPB41	IDA		Human	PMID:16254212
Cellular Component	GO:0030863	cortical cytoskeleton	Epb41	IDA		Mouse	PMID:18723693
Cellular Component	GO:0005737	cytoplasm	Epb41	IDA		Rat	PMID:11274145|RGD:11252102
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Epb41	IDA		Rat	PMID:15503808|RGD:11252101
Cellular Component	GO:0005829	cytosol	EPB41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0045171	intercellular bridge	EPB41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Epb41	IDA		Mouse	PMID:18723693
Cellular Component	GO:0072686	mitotic spindle	EPB41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	EPB41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	EPB41	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	EPB41	IMP		Human	PMID:6894932
Cellular Component	GO:0005886	plasma membrane	epb41b	IDA		Zfish	PMID:17569566
Cellular Component	GO:0014069	postsynaptic density	Epb41	IDA		Rat	PMID:11179975|RGD:11252106
Cellular Component	GO:0032991	protein-containing complex	EPB41	IDA		Human	PMID:16060676
Cellular Component	GO:0032991	protein-containing complex	EPB41	IMP		Human	PMID:20109190
Biological Process	GO:0035162	embryonic hemopoiesis	epb41b	IMP	ZFIN:ZDB-GENO-980202-1287	Zfish	PMID:9007251
Biological Process	GO:0035162	embryonic hemopoiesis	epb41b	IMP	ZFIN:ZDB-GENO-980202-69	Zfish	PMID:9007251
Biological Process	GO:0030218	erythrocyte differentiation	epb41b	IMP	ZFIN:ZDB-GENO-050819-6	Zfish	PMID:14608381
Biological Process	GO:0032092	positive regulation of protein binding	EPB41	IDA		Human	PMID:3693401
Biological Process	GO:0032092	positive regulation of protein binding	Epb41	IGI	MGI:MGI:98385	Mouse	PMID:20585040
Biological Process	GO:0032092	positive regulation of protein binding	Epb41	IGI	MGI:MGI:98387	Mouse	PMID:20585040
Biological Process	GO:1904778	positive regulation of protein localization to cell cortex	EPB41	IMP		Human	PMID:23870127
Biological Process	GO:0065003	protein-containing complex assembly	Epb41	IDA		Rat	PMID:11274145|RGD:11252102
Biological Process	GO:0051924	regulation of calcium ion transport	Epb41	IMP		Mouse	MGI:MGI:5496297|PMID:23460639
Biological Process	GO:1904478	regulation of intestinal absorption	Epb41	IMP		Mouse	MGI:MGI:5496297|PMID:23460639

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern