Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPB41L5
  • Mouse genes Epb41l5
  • Rat genes Epb41l5
  • Zfish genes epb41l5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epb41l5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EPB41L5	IPI	UniProtKB:P82279	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	EPB41L5	IPI	UniProtKB:P82279|UniProtKB:Q8N3R9	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	EPB41L5	IPI	UniProtKB:Q5IJ48	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	EPB41L5	IPI	UniProtKB:Q8N3R9	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	EPB41L5	IPI	UniProtKB:Q9BUF7	Human	PMID:17920587
Molecular Function	GO:0005515	protein binding	Epb41l5	IPI	PR:Q8VI36	Mouse	PMID:18794329
Molecular Function	GO:0005515	protein binding	Epb41l5	IPI	PR:P09055	Mouse	PMID:18794329
Molecular Function	GO:0005515	protein binding	Epb41l5	IPI	PR:P30999	Mouse	PMID:18794329
Molecular Function	GO:0019904	protein domain specific binding	Epb41l5	IPI	PR:P30999	Mouse	PMID:18794329
Cellular Component	GO:0005923	bicellular tight junction	epb41l5	IMP	ZFIN:ZDB-GENO-050822-1	Zfish	PMID:15084287
Cellular Component	GO:0031252	cell leading edge	Epb41l5	IDA		Mouse	PMID:18794329
Cellular Component	GO:0005829	cytosol	EPB41L5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005925	focal adhesion	Epb41l5	IDA		Mouse	PMID:18794329
Cellular Component	GO:0005654	nucleoplasm	EPB41L5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	EPB41L5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Epb41l5	IDA		Mouse	MGI:MGI:6467681|PMID:17920587
Cellular Component	GO:0005886	plasma membrane	Epb41l5	IDA		Mouse	PMID:18794329
Cellular Component	GO:0032991	protein-containing complex	epb41l5	IPI	ZFIN:ZDB-GENE-030404-2	Zfish	PMID:21262462
Cellular Component	GO:0032991	protein-containing complex	epb41l5	IPI	ZFIN:ZDB-GENE-050208-382	Zfish	PMID:21262462
Cellular Component	GO:0032991	protein-containing complex	epb41l5	IPI	ZFIN:ZDB-GENE-060610-1	Zfish	PMID:21262462
Cellular Component	GO:0032991	protein-containing complex	epb41l5	IPI	ZFIN:ZDB-GENE-060612-1	Zfish	PMID:21262462
Cellular Component	GO:0032587	ruffle membrane	Epb41l5	IDA		Mouse	PMID:18794329
Biological Process	GO:0030036	actin cytoskeleton organization	Epb41l5	IDA		Mouse	PMID:17507402
Biological Process	GO:0030036	actin cytoskeleton organization	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:17507402
Biological Process	GO:0031032	actomyosin structure organization	Epb41l5	IDA		Mouse	PMID:20103536
Biological Process	GO:0003383	apical constriction	Epb41l5	IDA		Mouse	PMID:20103536
Biological Process	GO:0048318	axial mesoderm development	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:15755804
Biological Process	GO:0048319	axial mesoderm morphogenesis	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:17507402
Biological Process	GO:0000904	cell morphogenesis involved in differentiation	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:20678497
Biological Process	GO:0071560	cellular response to transforming growth factor beta stimulus	Epb41l5	IDA		Mouse	PMID:18794329
Biological Process	GO:0021744	dorsal motor nucleus of vagus nerve development	epb41l5	IMP	ZFIN:ZDB-GENO-110321-4	Zfish	PMID:21262462
Biological Process	GO:0007398	ectoderm development	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0048048	embryonic eye morphogenesis	epb41l5	IMP	ZFIN:ZDB-GENO-050822-1	Zfish	PMID:15084287
Biological Process	GO:0048617	embryonic foregut morphogenesis	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	epb41l5	IMP	ZFIN:ZDB-GENO-110823-12	Zfish	PMID:20362667
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	epb41l5	IMP	ZFIN:ZDB-GENO-080822-1	Zfish	PMID:18190700
Biological Process	GO:0007492	endoderm development	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0003382	epithelial cell morphogenesis	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0001837	epithelial to mesenchymal transition	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:17507402
Biological Process	GO:0001837	epithelial to mesenchymal transition	Epb41l5	IMP		Mouse	PMID:18794329
Biological Process	GO:0035088	establishment or maintenance of apical/basal cell polarity	epb41l5	IMP	ZFIN:ZDB-GENO-050822-1	Zfish	PMID:15084287
Biological Process	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	epb41l5	IMP	ZFIN:ZDB-GENO-080822-1	Zfish	PMID:18190700
Biological Process	GO:0001701	in utero embryonic development	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0001822	kidney development	epb41l5	IMP	ZFIN:ZDB-GENO-040519-1	Zfish	PMID:16102746
Biological Process	GO:0070986	left/right axis specification	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:20678497
Biological Process	GO:0045199	maintenance of epithelial cell apical/basal polarity	epb41l5	IMP	ZFIN:ZDB-GENO-110321-4	Zfish	PMID:21262462
Biological Process	GO:0007498	mesoderm development	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0007509	mesoderm migration involved in gastrulation	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0032091	negative regulation of protein binding	Epb41l5	IDA		Mouse	PMID:18794329
Biological Process	GO:0001839	neural plate morphogenesis	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:17507402
Biological Process	GO:0001839	neural plate morphogenesis	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0048339	paraxial mesoderm development	Epb41l5	IMP	MGI:MGI:3578147	Mouse	PMID:15755804
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0010634	positive regulation of epithelial cell migration	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	epb41l5	IEP		Zfish	PMID:21262462
Biological Process	GO:0032092	positive regulation of protein binding	Epb41l5	IDA		Mouse	PMID:18794329
Biological Process	GO:0010608	post-transcriptional regulation of gene expression	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0031503	protein-containing complex localization	epb41l5	IMP	ZFIN:ZDB-GENO-110321-4	Zfish	PMID:21262462
Biological Process	GO:0070201	regulation of establishment of protein localization	Epb41l5	IDA		Mouse	PMID:18794329
Biological Process	GO:0032525	somite rostral/caudal axis specification	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0001756	somitogenesis	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0006931	substrate-dependent cell migration, cell attachment to substrate	Epb41l5	IMP	MGI:MGI:3822451	Mouse	PMID:18794329
Biological Process	GO:0009826	unidimensional cell growth	Epb41l5	IDA		Mouse	PMID:20103536

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern