Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPC1
  • Mouse genes Epc1
  • Rat genes Epc1
  • Zfish genes epc1a,epc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140463	chromatin-protein adaptor activity	EPC1	IDA		Human	PMID:32209463
Molecular Function	GO:0140767	enzyme-substrate adaptor activity	EPC1	IDA		Human	PMID:28694333
Molecular Function	GO:0140677	molecular function activator activity	EPC1	IDA		Human	PMID:32209463
Molecular Function	GO:0005515	protein binding	EPC1	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EPC1	IPI	UniProtKB:Q6NUQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EPC1	IPI	UniProtKB:Q05BQ5	Human	PMID:27153538
Molecular Function	GO:0005515	protein binding	EPC1	IPI	UniProtKB:Q9H0E9	Human	PMID:27153538
Molecular Function	GO:0005515	protein binding	EPC1	IPI	UniProtKB:Q6NUQ1	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EPC1	IPI	UniProtKB:Q05BQ5	Human	PMID:32209463
Molecular Function	GO:0005515	protein binding	Epc1	IPI	RGD:631347	Rat	PMID:22398275|RGD:9587795
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	EPC1	IDA		Human	PMID:27153538
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	EPC1	IDA		Human	PMID:14966270
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	EPC1	IDA		Human	PMID:32209463
Cellular Component	GO:0031965	nuclear membrane	EPC1	IDA		Human	PMID:10976108
Cellular Component	GO:0005654	nucleoplasm	EPC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	EPC1	IDA		Human	PMID:10976108
Cellular Component	GO:0000786	nucleosome	EPC1	IDA		Human	PMID:27153538
Cellular Component	GO:0005634	nucleus	EPC1	IDA		Human	PMID:10976108
Cellular Component	GO:0005634	nucleus	EPC1	IDA		Human	PMID:17192267
Cellular Component	GO:0032777	Piccolo NuA4 histone acetyltransferase complex	EPC1	IDA		Human	PMID:14966270
Cellular Component	GO:0035861	site of double-strand break	EPC1	IDA		Human	PMID:27153538
Biological Process	GO:0000724	double-strand break repair via homologous recombination	EPC1	IDA		Human	PMID:27153538
Biological Process	GO:0016573	histone acetylation	EPC1	IDA		Human	PMID:14966270
Biological Process	GO:0043968	histone H2A acetylation	EPC1	IDA		Human	PMID:27153538
Biological Process	GO:0043967	histone H4 acetylation	EPC1	IDA		Human	PMID:27153538
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	EPC1	IDA		Human	PMID:10976108
Biological Process	GO:0045814	negative regulation of gene expression, epigenetic	EPC1	IDA		Human	PMID:10976108
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	EPC1	IDA		Human	PMID:10976108
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	EPC1	IDA		Human	PMID:27153538
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	EPC1	IDA		Human	PMID:10976108
Biological Process	GO:0051726	regulation of cell cycle	EPC1	IMP		Human	PMID:27153538
Biological Process	GO:0035092	sperm DNA condensation	EPC1	IMP		Human	PMID:28694333
Biological Process	GO:0007286	spermatid development	EPC1	IMP		Human	PMID:28694333
Biological Process	GO:0035886	vascular associated smooth muscle cell differentiation	Epc1	IEP		Rat	PMID:22398275|RGD:9587795

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern