Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPHA7
  • Mouse genes Epha7
  • Rat genes Epha7
  • Zfish genes epha7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epha7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	Epha7	IMP		Mouse	MGI:MGI:5294300|PMID:16301174
Molecular Function	GO:0045499	chemorepellent activity	Epha7	IDA		Mouse	PMID:15996548
Molecular Function	GO:0046875	ephrin receptor binding	Epha7	IDA		Rat	PMID:10366629|RGD:2301959
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	Epha7	IDA		Mouse	MGI:MGI:2182552|PMID:11089974
Molecular Function	GO:0019838	growth factor binding	Epha7	IPI	UniProtKB:P52797	Mouse	MGI:MGI:6478053|PMID:22568954
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P29317	Human	PMID:22036564
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P29320	Human	PMID:22036564
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P52793	Human	PMID:22036564
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P07333	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P29317	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P29320	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P29323	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:P54760	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	EPHA7	IPI	UniProtKB:Q16288	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Epha7	IPI	UniProtKB:O08543	Mouse	MGI:MGI:5426777|PMID:19036963
Molecular Function	GO:0005515	protein binding	Epha7	IPI	UniProtKB:O08543	Mouse	MGI:MGI:2182552|PMID:11089974
Molecular Function	GO:0005515	protein binding	Epha7	IPI	UniProtKB:O08992	Rat	PMID:9883737|RGD:8554504
Molecular Function	GO:0005515	protein binding	Epha7	IPI	UniProtKB:Q62083	Rat	PMID:9883737|RGD:8554504
Molecular Function	GO:0005515	protein binding	Epha7	IPI	UniProtKB:Q925T6	Rat	PMID:9883737|RGD:8554504
Molecular Function	GO:0004713	protein tyrosine kinase activity	Epha7	IDA		Rat	PMID:9883737|RGD:8554504
Cellular Component	GO:0030425	dendrite	Epha7	IDA		Rat	PMID:10792438|RGD:1300471
Cellular Component	GO:0098978	glutamatergic synapse	Epha7	IDA		Mouse	PMID:24707048
Cellular Component	GO:0098978	glutamatergic synapse	Epha7	IMP		Mouse	PMID:24707048
Cellular Component	GO:0098978	glutamatergic synapse	Epha7	IDA		Rat	PMID:26780036|RGD:13702137
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Epha7	IDA		Rat	PMID:26780036|RGD:13702137
Cellular Component	GO:0031594	neuromuscular junction	Epha7	IDA		Rat	PMID:11414792|RGD:2301728
Cellular Component	GO:0043025	neuronal cell body	Epha7	IDA		Rat	PMID:10792438|RGD:1300471
Cellular Component	GO:0005886	plasma membrane	EPHA7	IDA		Human	PMID:16862074
Cellular Component	GO:0098839	postsynaptic density membrane	Epha7	IDA		Rat	PMID:26780036|RGD:13702137
Cellular Component	GO:0045211	postsynaptic membrane	Epha7	IDA		Rat	PMID:9922461|RGD:2301960
Cellular Component	GO:0099634	postsynaptic specialization membrane	Epha7	IDA		Rat	PMID:11414792|RGD:2301728
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Epha7	IDA		Rat	PMID:26780036|RGD:13702137
Biological Process	GO:0007420	brain development	Epha7	IMP		Mouse	MGI:MGI:3582020|PMID:15902206
Biological Process	GO:0048755	branching morphogenesis of a nerve	Epha7	IMP	MGI:MGI:3583808	Mouse	PMID:15996548
Biological Process	GO:0048013	ephrin receptor signaling pathway	EPHA7	IDA		Human	PMID:17726105
Biological Process	GO:0048013	ephrin receptor signaling pathway	Epha7	IDA		Mouse	MGI:MGI:2182552|PMID:11089974
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Epha7	IDA		Mouse	PMID:24707048
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Epha7	IMP		Mouse	PMID:24707048
Biological Process	GO:0048671	negative regulation of collateral sprouting	Epha7	IDA		Mouse	MGI:MGI:5426777|PMID:19036963
Biological Process	GO:0051964	negative regulation of synapse assembly	Epha7	IDA		Mouse	MGI:MGI:5426777|PMID:19036963
Biological Process	GO:0072178	nephric duct morphogenesis	Epha7	IGI	MGI:MGI:98277	Mouse	PMID:25139858
Biological Process	GO:0051402	neuron apoptotic process	Epha7	IMP		Mouse	PMID:15902206
Biological Process	GO:0016310	phosphorylation	Epha7	IDA		Rat	PMID:9883737|RGD:8554504
Biological Process	GO:0043065	positive regulation of apoptotic process	Epha7	IMP		Rat	PMID:16983667|RGD:2301957
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Epha7	IMP		Mouse	PMID:15902206
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Epha7	IDA		Mouse	MGI:MGI:5426777|PMID:19036963
Biological Process	GO:0022407	regulation of cell-cell adhesion	Epha7	IDA		Mouse	MGI:MGI:2182552|PMID:11089974
Biological Process	GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	Epha7	IDA		Mouse	MGI:MGI:3582020|PMID:15902206
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	EPHA7	IDA		Human	PMID:17726105
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	EPHA7	IDA		Human	PMID:17726105
Biological Process	GO:0050730	regulation of peptidyl-tyrosine phosphorylation	Epha7	IDA		Mouse	MGI:MGI:2182552|PMID:11089974
Biological Process	GO:0099175	regulation of postsynapse organization	Epha7	IDA		Mouse	PMID:24707048
Biological Process	GO:0099175	regulation of postsynapse organization	Epha7	IMP		Mouse	PMID:24707048
Biological Process	GO:0031952	regulation of protein autophosphorylation	Epha7	IDA		Mouse	MGI:MGI:2182552|PMID:11089974
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Epha7	IMP	MGI:MGI:3583808	Mouse	PMID:15996548

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern