Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPHA8
  • Mouse genes Epha8
  • Rat genes Epha8
  • Zfish genes epha8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epha8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	Epha8	IDA		Mouse	MGI:MGI:5294313|PMID:11416136
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	Epha8	IDA		Mouse	MGI:MGI:85724|PMID:9053851
Molecular Function	GO:0019838	growth factor binding	Epha8	IPI	UniProtKB:P52793	Mouse	MGI:MGI:6478053|PMID:22568954
Molecular Function	GO:0005515	protein binding	Epha8	IPI	UniProtKB:P48736	Mouse	MGI:MGI:5294313|PMID:11416136
Molecular Function	GO:0005515	protein binding	Epha8	IPI	UniProtKB:P06241	Mouse	MGI:MGI:5294316|PMID:10498895
Molecular Function	GO:0005515	protein binding	Epha8	IPI	UniProtKB:P59672|UniProtKB:Q7Z6G8	Mouse	MGI:MGI:3768579|PMID:17875921
Molecular Function	GO:0005515	protein binding	Epha8	IPI	UniProtKB:O08543|UniProtKB:O08545|UniProtKB:P52801	Mouse	MGI:MGI:85724|PMID:9053851
Molecular Function	GO:0005515	protein binding	Epha8	IPI	PR:P59672	Mouse	PMID:20100865
Cellular Component	GO:0043005	neuron projection	Epha8	IDA		Mouse	MGI:MGI:3768579|PMID:17875921
Cellular Component	GO:0005886	plasma membrane	Epha8	IDA		Mouse	MGI:MGI:85724|PMID:9053851
Biological Process	GO:0007411	axon guidance	Epha8	IMP		Mouse	MGI:MGI:892883|PMID:9214628
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Epha8	IDA		Mouse	PMID:23242526
Biological Process	GO:0048013	ephrin receptor signaling pathway	Epha8	IDA		Mouse	MGI:MGI:85724|PMID:9053851
Biological Process	GO:0048013	ephrin receptor signaling pathway	Epha8	IDA		Mouse	MGI:MGI:3768579|PMID:17875921
Biological Process	GO:0048013	ephrin receptor signaling pathway	Epha8	IDA		Mouse	MGI:MGI:5294313|PMID:11416136
Biological Process	GO:0031175	neuron projection development	Epha8	IDA		Mouse	MGI:MGI:5294303|PMID:15782114
Biological Process	GO:0016322	neuron remodeling	Epha8	IDA		Mouse	MGI:MGI:3768579|PMID:17875921
Biological Process	GO:0043410	positive regulation of MAPK cascade	Epha8	IDA		Mouse	MGI:MGI:5294303|PMID:15782114
Biological Process	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	Epha8	IDA		Mouse	MGI:MGI:5294313|PMID:11416136
Biological Process	GO:0046777	protein autophosphorylation	Epha8	IDA		Mouse	MGI:MGI:5294313|PMID:11416136
Biological Process	GO:0046777	protein autophosphorylation	Epha8	IDA		Mouse	MGI:MGI:5294316|PMID:10498895
Biological Process	GO:0030155	regulation of cell adhesion	Epha8	IDA		Mouse	MGI:MGI:5294316|PMID:10498895
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	Epha8	IDA		Mouse	MGI:MGI:5294313|PMID:11416136
Biological Process	GO:0006929	substrate-dependent cell migration	Epha8	IDA		Mouse	MGI:MGI:3768579|PMID:17875921

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern