Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ephb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes EPHB1
- Mouse genes Ephb1
- Rat genes Ephb1
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ephb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	Ephb1	IDA		Mouse	PMID:11532925
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:Q14451	Human	PMID:12223469
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:P12931	Human	PMID:12925710
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:P29353	Human	PMID:12925710
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:P62993	Human	PMID:12925710
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:P22681	Human	PMID:18034775
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:P62993	Human	PMID:8798570
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:Q13322	Human	PMID:8798570
Molecular Function	GO:0005515	protein binding	EPHB1	IPI	UniProtKB:P24666	Human	PMID:9499402
Molecular Function	GO:0005515	protein binding	Ephb1	IPI	UniProtKB:Q91V57	Mouse	MGI:MGI:3767884\|PMID:17785183
Molecular Function	GO:0005515	protein binding	Ephb1	IPI	UniProtKB:P22682	Mouse	MGI:MGI:5294293\|PMID:18034775
Molecular Function	GO:0005515	protein binding	Ephb1	IPI	UniProtKB:P05480\|UniProtKB:P98083\|UniProtKB:Q60631	Mouse	MGI:MGI:5294305\|PMID:12925710
Molecular Function	GO:0004713	protein tyrosine kinase activity	Ephb1	IDA		Rat	PMID:2017163\|RGD:632705
Molecular Function	GO:0004713	protein tyrosine kinase activity	Ephb1	IMP		Rat	PMID:2485255\|RGD:632706
Molecular Function	GO:0044877	protein-containing complex binding	Ephb1	IPI	PR:O55033	Mouse	PMID:17310244
Molecular Function	GO:0044877	protein-containing complex binding	Ephb1	IPI	PR:Q68FF6	Mouse	PMID:17310244
Molecular Function	GO:0005005	transmembrane-ephrin receptor activity	EPHB1	IDA		Human	PMID:18034775
Cellular Component	GO:0030424	axon	Ephb1	IDA		Mouse	PMID:16701205
Cellular Component	GO:0005737	cytoplasm	Ephb1	IDA		Mouse	PMID:12093895
Cellular Component	GO:0005829	cytosol	EPHB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0031901	early endosome membrane	EPHB1	IDA		Human	PMID:18034775
Cellular Component	GO:0005783	endoplasmic reticulum	EPHB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	EPHB1	HDA		Human	PMID:20458337
Cellular Component	GO:0032433	filopodium tip	Ephb1	IDA		Mouse	PMID:24305805
Cellular Component	GO:0098978	glutamatergic synapse	Ephb1	IDA		Mouse	PMID:19523204
Cellular Component	GO:0098978	glutamatergic synapse	Ephb1	IEP		Mouse	PMID:19523204
Cellular Component	GO:0098978	glutamatergic synapse	Ephb1	IMP		Mouse	PMID:19523204
Cellular Component	GO:0016020	membrane	Ephb1	IDA		Mouse	PMID:12093895
Cellular Component	GO:0045121	membrane raft	Ephb1	IDA		Mouse	PMID:15502157
Cellular Component	GO:0005886	plasma membrane	EPHB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	EPHB1	IDA		Human	PMID:18034775
Biological Process	GO:0001525	angiogenesis	EPHB1	IDA		Human	PMID:9499402
Biological Process	GO:0007411	axon guidance	Ephb1	IMP	MGI:MGI:2677312	Mouse	PMID:12971893
Biological Process	GO:0007411	axon guidance	Ephb1	IMP		Mouse	PMID:24997765
Biological Process	GO:0007411	axon guidance	Ephb1	IMP	MGI:MGI:2677305	Mouse	PMID:16701205
Biological Process	GO:0007411	axon guidance	Ephb1	IMP	MGI:MGI:2677305	Mouse	PMID:12971893
Biological Process	GO:0007411	axon guidance	Ephb1	IDA		Mouse	PMID:11532925
Biological Process	GO:0048593	camera-type eye morphogenesis	Ephb1	IMP	MGI:MGI:2677305	Mouse	PMID:12971893
Biological Process	GO:0060326	cell chemotaxis	EPHB1	IDA		Human	PMID:12925710
Biological Process	GO:0060326	cell chemotaxis	Ephb1	IMP		Mouse	MGI:MGI:3765131\|PMID:18057206
Biological Process	GO:0031589	cell-substrate adhesion	EPHB1	IDA		Human	PMID:9430661
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Ephb1	IDA		Mouse	PMID:12971893
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Ephb1	IMP	MGI:MGI:2677312	Mouse	PMID:12971893
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Ephb1	IMP	MGI:MGI:2677305	Mouse	PMID:12971893
Biological Process	GO:0021545	cranial nerve development	Ephb1	IMP	MGI:MGI:2677305	Mouse	PMID:12971893
Biological Process	GO:0060996	dendritic spine development	Ephb1	IMP		Mouse	MGI:MGI:2683349\|PMID:14691139
Biological Process	GO:0060996	dendritic spine development	Ephb1	IGI	UniProtKB:D4A3M8	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0060996	dendritic spine development	Ephb1	IGI	UniProtKB:Q9Z272	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0060997	dendritic spine morphogenesis	Ephb1	IMP		Mouse	MGI:MGI:2683349\|PMID:14691139
Biological Process	GO:0060997	dendritic spine morphogenesis	Ephb1	IMP		Mouse	PMID:17310244
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Ephb1	IMP		Mouse	MGI:MGI:5294537\|PMID:19025592
Biological Process	GO:0048013	ephrin receptor signaling pathway	EPHB1	IDA		Human	PMID:12925710
Biological Process	GO:0048013	ephrin receptor signaling pathway	EPHB1	IDA		Human	PMID:18034775
Biological Process	GO:0048013	ephrin receptor signaling pathway	Ephb1	IDA		Mouse	PMID:17310244
Biological Process	GO:0030010	establishment of cell polarity	Ephb1	IMP		Mouse	MGI:MGI:3765131\|PMID:18057206
Biological Process	GO:0021934	hindbrain tangential cell migration	Ephb1	IMP		Rat	PMID:28276447\|RGD:127285619
Biological Process	GO:0001771	immunological synapse formation	Ephb1	IGI	UniProtKB:D4A3M8	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0001771	immunological synapse formation	Ephb1	IGI	UniProtKB:Q9Z272	Rat	PMID:17310244\|RGD:10047256
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ephb1	IDA		Mouse	PMID:19523204
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ephb1	IMP		Mouse	PMID:19523204
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ephb1	IEP		Mouse	PMID:19523204
Biological Process	GO:1902725	negative regulation of satellite cell differentiation	Ephb1	IMP		Mouse	MGI:MGI:5897527\|PMID:27446912
Biological Process	GO:1902723	negative regulation of skeletal muscle satellite cell proliferation	Ephb1	IMP		Mouse	MGI:MGI:5897527\|PMID:27446912
Biological Process	GO:0061351	neural precursor cell proliferation	Ephb1	IMP		Mouse	MGI:MGI:3765131\|PMID:18057206
Biological Process	GO:0022008	neurogenesis	Ephb1	IMP		Mouse	MGI:MGI:3765131\|PMID:18057206
Biological Process	GO:0021631	optic nerve morphogenesis	Ephb1	IMP	MGI:MGI:2677305	Mouse	PMID:12971893
Biological Process	GO:0051965	positive regulation of synapse assembly	Ephb1	IMP		Mouse	MGI:MGI:2683349\|PMID:14691139
Biological Process	GO:0046777	protein autophosphorylation	EPHB1	IDA		Human	PMID:18034775
Biological Process	GO:0046777	protein autophosphorylation	Ephb1	IDA		Rat	PMID:2017163\|RGD:632705
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	EPHB1	IDA		Human	PMID:12925710
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	EPHB1	IDA		Human	PMID:18034775
Biological Process	GO:0046328	regulation of JNK cascade	EPHB1	IDA		Human	PMID:9430661
Biological Process	GO:1901214	regulation of neuron death	EPHB1	IMP		Human	PMID:21085126
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Ephb1	IDA		Mouse	PMID:12971893
Biological Process	GO:0014719	skeletal muscle satellite cell activation	Ephb1	IMP		Mouse	MGI:MGI:5897527\|PMID:27446912

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.