Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPHB3
  • Mouse genes Ephb3
  • Rat genes Ephb3
  • Zfish genes ephb3a,ephb3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ephb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008046	axon guidance receptor activity	Ephb3	IDA		Mouse	PMID:11532925
Molecular Function	GO:0005003	ephrin receptor activity	EPHB3	IDA		Human	PMID:15536074
Molecular Function	GO:0005003	ephrin receptor activity	EPHB3	IDA		Human	PMID:8397371
Molecular Function	GO:0005515	protein binding	EPHB3	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EPHB3	IPI	UniProtKB:P37235	Human	PMID:32296183
Cellular Component	GO:0005886	plasma membrane	EPHB3	IDA		Human	PMID:15536074
Cellular Component	GO:0005886	plasma membrane	EPHB3	IDA		Human	PMID:8397371
Biological Process	GO:0001525	angiogenesis	Ephb3	IMP		Mouse	MGI:MGI:1331270|PMID:9990854
Biological Process	GO:0007411	axon guidance	Ephb3	IMP		Mouse	MGI:MGI:84499|PMID:8947026
Biological Process	GO:0007411	axon guidance	Ephb3	IMP		Mouse	MGI:MGI:1859095|PMID:10839360
Biological Process	GO:0007411	axon guidance	Ephb3	IDA		Mouse	PMID:11532925
Biological Process	GO:0007413	axonal fasciculation	Ephb3	IMP		Mouse	MGI:MGI:84499|PMID:8947026
Biological Process	GO:0016477	cell migration	EPHB3	IDA		Human	PMID:15536074
Biological Process	GO:0016477	cell migration	Ephb3	IMP		Mouse	MGI:MGI:2388849|PMID:12408869
Biological Process	GO:0021952	central nervous system projection neuron axonogenesis	Ephb3	IDA		Mouse	PMID:12971893
Biological Process	GO:0022038	corpus callosum development	Ephb3	IMP		Mouse	MGI:MGI:84499|PMID:8947026
Biological Process	GO:0060996	dendritic spine development	Ephb3	IMP		Mouse	MGI:MGI:2683349|PMID:14691139
Biological Process	GO:0060997	dendritic spine morphogenesis	Ephb3	IMP		Mouse	MGI:MGI:2683349|PMID:14691139
Biological Process	GO:0048546	digestive tract morphogenesis	Ephb3	IMP		Mouse	MGI:MGI:2388849|PMID:12408869
Biological Process	GO:1990402	embryonic liver development	ephb3b	IMP	ZFIN:ZDB-MRPHLNO-170201-4	Zfish	PMID:27825440
Biological Process	GO:0048013	ephrin receptor signaling pathway	EPHB3	IDA		Human	PMID:15536074
Biological Process	GO:0048013	ephrin receptor signaling pathway	EPHB3	IDA		Human	PMID:8397371
Biological Process	GO:0051965	positive regulation of synapse assembly	Ephb3	IMP		Mouse	MGI:MGI:2683349|PMID:14691139
Biological Process	GO:0046777	protein autophosphorylation	EPHB3	IDA		Human	PMID:15536074
Biological Process	GO:0046777	protein autophosphorylation	EPHB3	IDA		Human	PMID:8397371
Biological Process	GO:0050770	regulation of axonogenesis	Ephb3	IDA		Mouse	MGI:MGI:3759704|PMID:17719550
Biological Process	GO:0022407	regulation of cell-cell adhesion	EPHB3	IDA		Human	PMID:8397371
Biological Process	GO:0043087	regulation of GTPase activity	EPHB3	IDA		Human	PMID:15536074
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Ephb3	IDA		Mouse	PMID:12971893
Biological Process	GO:0060021	roof of mouth development	Ephb3	IMP		Mouse	MGI:MGI:84499|PMID:8947026
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	EPHB3	IDA		Human	PMID:15536074
Biological Process	GO:0048538	thymus development	Ephb3	IMP		Mouse	MGI:MGI:4366231|PMID:19598115
Biological Process	GO:0001655	urogenital system development	Ephb3	IMP		Mouse	MGI:MGI:3047196|PMID:15223334

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern