Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPHB6
  • Mouse genes Ephb6
  • Rat genes Ephb6
  • Zfish genes ephb6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ephb6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EPHB6	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	EPHB6	IPI	UniProtKB:P08238	Human	PMID:35384245
Cellular Component	GO:0009986	cell surface	Ephb6	IDA		Mouse	PMID:15599401
Biological Process	GO:0050798	activated T cell proliferation	Ephb6	IMP	MGI:MGI:3522020	Mouse	PMID:15599401
Biological Process	GO:0001816	cytokine production	Ephb6	IMP	MGI:MGI:3522020	Mouse	PMID:15599401
Biological Process	GO:0032092	positive regulation of protein binding	Ephb6	IMP	MGI:MGI:3522020	Mouse	PMID:15599401
Biological Process	GO:2000525	positive regulation of T cell costimulation	Ephb6	IGI	MGI:MGI:104757	Mouse	PMID:15599401
Biological Process	GO:0002456	T cell mediated immunity	Ephb6	IMP	MGI:MGI:3522020	Mouse	PMID:15599401
Biological Process	GO:0001806	type IV hypersensitivity	Ephb6	IMP	MGI:MGI:3522020	Mouse	PMID:15599401

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern