Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPM2A
  • Mouse genes Epm2a
  • Rat genes Epm2a
  • Zfish genes epm2a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epm2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019203	carbohydrate phosphatase activity	Epm2a	IDA		Mouse	PMID:18040046
Molecular Function	GO:0019203	carbohydrate phosphatase activity	Epm2a	IMP		Mouse	PMID:18040046
Molecular Function	GO:0004373	glycogen (starch) synthase activity	Epm2a	IEP		Mouse	PMID:18852261
Molecular Function	GO:0042802	identical protein binding	Epm2a	IPI	PR:Q9WUA5	Mouse	PMID:16971387
Molecular Function	GO:0016791	phosphatase activity	Epm2a	IDA		Mouse	PMID:24430976
Molecular Function	GO:0004721	phosphoprotein phosphatase activity	Epm2a	IDA		Mouse	PMID:16971387
Molecular Function	GO:0030247	polysaccharide binding	Epm2a	IDA		Mouse	PMID:15102711
Molecular Function	GO:0005515	protein binding	EPM2A	IPI	UniProtKB:O95210	Human	PMID:24837458
Molecular Function	GO:0005515	protein binding	Epm2a	IPI	UniProtKB:Q6VVB1	Mouse	MGI:MGI:5501016|PMID:22578008
Molecular Function	GO:0005515	protein binding	Epm2a	IPI	UniProtKB:Q9WV60	Mouse	MGI:MGI:3663202|PMID:16959610
Molecular Function	GO:0005515	protein binding	Epm2a	IPI	PR:Q9WVS6	Mouse	PMID:28063983
Molecular Function	GO:0004722	protein serine/threonine phosphatase activity	Epm2a	IDA		Mouse	PMID:16971387
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	Epm2a	IDA		Mouse	PMID:15541350
Molecular Function	GO:2001070	starch binding	Epm2a	IDA		Mouse	PMID:15102711
Cellular Component	GO:0005737	cytoplasm	Epm2a	IDA		Mouse	PMID:17908927
Cellular Component	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane	Epm2a	IDA		Mouse	PMID:15102711
Cellular Component	GO:0005829	cytosol	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:22669944
Cellular Component	GO:0030425	dendrite	Epm2a	IDA		Mouse	PMID:15102711
Cellular Component	GO:0005634	nucleus	Epm2a	IDA		Mouse	PMID:17908927
Cellular Component	GO:0043204	perikaryon	Epm2a	IDA		Mouse	PMID:15102711
Biological Process	GO:0000045	autophagosome assembly	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24430976
Biological Process	GO:0006914	autophagy	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24914213
Biological Process	GO:0006816	calcium ion transport	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:28063983
Biological Process	GO:0046835	carbohydrate phosphorylation	Epm2a	IMP	MGI:2182627	Mouse	PMID:18852261
Biological Process	GO:0014009	glial cell proliferation	Epm2a	IGI	MGI:MGI:104993	Mouse	PMID:28973665
Biological Process	GO:0005978	glycogen biosynthetic process	Epm2a	IMP		Mouse	PMID:17118331
Biological Process	GO:0005978	glycogen biosynthetic process	Epm2a	IMP	MGI:MGI:6118039	Mouse	PMID:31042462
Biological Process	GO:0005978	glycogen biosynthetic process	Epm2a	IDA		Mouse	PMID:18040046
Biological Process	GO:0005978	glycogen biosynthetic process	Epm2a	IGI	MGI:MGI:2145264	Mouse	PMID:28536304
Biological Process	GO:0005978	glycogen biosynthetic process	Epm2a	IMP		Mouse	PMID:28536304
Biological Process	GO:0005977	glycogen metabolic process	Epm2a	IMP	MGI:2182627	Mouse	PMID:18852261
Biological Process	GO:0005977	glycogen metabolic process	Epm2a	IGI	MGI:MGI:1858229	Mouse	PMID:21552327
Biological Process	GO:0005977	glycogen metabolic process	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:25416783
Biological Process	GO:0005977	glycogen metabolic process	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24914213
Biological Process	GO:0005977	glycogen metabolic process	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:23663739
Biological Process	GO:0005977	glycogen metabolic process	Epm2a	IGI	MGI:MGI:104993	Mouse	PMID:28973665
Biological Process	GO:0046959	habituation	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:12019206
Biological Process	GO:0015813	L-glutamate transmembrane transport	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:26976331
Biological Process	GO:0043170	macromolecule metabolic process	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:23663739
Biological Process	GO:0007005	mitochondrion organization	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:28063983
Biological Process	GO:0045786	negative regulation of cell cycle	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:18824542
Biological Process	GO:0010629	negative regulation of gene expression	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:18824542
Biological Process	GO:0033137	negative regulation of peptidyl-serine phosphorylation	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:18824542
Biological Process	GO:0032007	negative regulation of TOR signaling	EPM2A	IMP		Human	PMID:20453062
Biological Process	GO:0007399	nervous system development	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:12019206
Biological Process	GO:0016239	positive regulation of macroautophagy	EPM2A	IMP		Human	PMID:20453062
Biological Process	GO:0016239	positive regulation of macroautophagy	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:20453062
Biological Process	GO:0016239	positive regulation of macroautophagy	Epm2a	IGI	MGI:MGI:102548	Mouse	PMID:20453062
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24914213
Biological Process	GO:0001558	regulation of cell growth	Epm2a	IMP		Mouse	PMID:18824542
Biological Process	GO:0010468	regulation of gene expression	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:28063983
Biological Process	GO:0010468	regulation of gene expression	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24914213
Biological Process	GO:0010468	regulation of gene expression	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:27107699
Biological Process	GO:2000465	regulation of glycogen (starch) synthase activity	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:18040046
Biological Process	GO:0042325	regulation of phosphorylation	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:18040046
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:27107699
Biological Process	GO:0042306	regulation of protein import into nucleus	Epm2a	IDA		Mouse	PMID:16971387
Biological Process	GO:0045859	regulation of protein kinase activity	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24914213
Biological Process	GO:1903076	regulation of protein localization to plasma membrane	Epm2a	IGI	MGI:MGI:2145264	Mouse	PMID:26976331
Biological Process	GO:0001932	regulation of protein phosphorylation	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:24914213
Biological Process	GO:0001932	regulation of protein phosphorylation	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:18824542
Biological Process	GO:0031396	regulation of protein ubiquitination	Epm2a	IGI	MGI:MGI:2145264	Mouse	PMID:26976331
Biological Process	GO:1904666	regulation of ubiquitin protein ligase activity	Epm2a	IMP	MGI:MGI:2182627	Mouse	PMID:28063983
Biological Process	GO:0016055	Wnt signaling pathway	Epm2a	IMP		Mouse	PMID:16971387

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern