Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EPOR
  • Mouse genes Epor
  • Rat genes Epor
  • Zfish genes epor
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Epor

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004900	erythropoietin receptor activity	EPOR	IDA		Human	PMID:2163696
Molecular Function	GO:0004900	erythropoietin receptor activity	Epor	IDA		Rat	PMID:7684373|RGD:728583
Molecular Function	GO:0042802	identical protein binding	EPOR	IPI	UniProtKB:P19235	Human	PMID:16116438
Molecular Function	GO:0042802	identical protein binding	EPOR	IPI	UniProtKB:P19235	Human	PMID:21058338
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:O14508	Human	PMID:11781573
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:Q62225	Human	PMID:11781573
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:Q8WWM7	Human	PMID:11784712
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P18031	Human	PMID:14527337
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P16885	Human	PMID:15644415
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:Q62225	Human	PMID:15644415
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:Q6ZWK4	Human	PMID:25092874
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P01588:PRO_0000008401	Human	PMID:26481148
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P01588	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P29350	Human	PMID:7228577
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P29350	Human	PMID:7528537
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P29350	Human	PMID:7528577
Molecular Function	GO:0005515	protein binding	EPOR	IPI	UniProtKB:P01588	Human	PMID:9774108
Molecular Function	GO:0005515	protein binding	Epor	IPI	UniProtKB:Q62077|UniProtKB:Q8CIH5	Mouse	MGI:MGI:3689794|PMID:15953601
Molecular Function	GO:0005515	protein binding	Epor	IPI	UniProtKB:Q62120	Mouse	MGI:MGI:5508621|PMID:17024180
Molecular Function	GO:0005515	protein binding	Epor	IPI	UniProtKB:Q62120	Mouse	MGI:MGI:5508729|PMID:21362419
Molecular Function	GO:0005515	protein binding	Epor	IPI	PR:Q8BH75	Mouse	PMID:18495327
Cellular Component	GO:0009986	cell surface	Epor	IDA		Rat	PMID:27587253|RGD:149735329
Cellular Component	GO:0005737	cytoplasm	Epor	IDA		Rat	PMID:17554621|RGD:11041649
Cellular Component	GO:0009897	external side of plasma membrane	Epor	IDA		Rat	PMID:21649646|RGD:10401062
Cellular Component	GO:0016607	nuclear speck	EPOR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	EPOR	IDA		Human	GO_REF:0000052
Biological Process	GO:0007568	aging	Epor	IEP		Rat	PMID:19330822|RGD:2313640
Biological Process	GO:0007420	brain development	Epor	IMP	MGI:MGI:1857575	Mouse	PMID:11807041
Biological Process	GO:1904374	cellular response to kainic acid	Epor	IEP		Rat	PMID:18711747|RGD:11041671
Biological Process	GO:0046697	decidualization	Epor	IDA		Mouse	PMID:17300687
Biological Process	GO:0009790	embryo development	Epor	IDA		Mouse	PMID:17300687
Biological Process	GO:0007507	heart development	Epor	IMP	MGI:MGI:1857575	Mouse	PMID:11807041
Biological Process	GO:0030097	hemopoiesis	epor	IMP	ZFIN:ZDB-MRPHLNO-080325-2,ZFIN:ZDB-MRPHLNO-080325-3	Zfish	PMID:17579187
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	Epor	IMP		Rat	PMID:23636173|RGD:10401070
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Epor	IMP		Rat	PMID:12451129|RGD:628490
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Epor	IMP		Rat	PMID:18711747|RGD:11041671
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	Epor	IMP		Rat	PMID:10489101|RGD:11041656
Biological Process	GO:0008284	positive regulation of cell population proliferation	Epor	IMP		Rat	PMID:21749867|RGD:10400910
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	Epor	IDA		Rat	PMID:7684373|RGD:728583
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Epor	IMP		Rat	PMID:21749867|RGD:10400910
Biological Process	GO:0010976	positive regulation of neuron projection development	Epor	IMP		Rat	PMID:22469063|RGD:10401068
Biological Process	GO:0048793	pronephros development	epor	IMP	ZFIN:ZDB-CRISPR-180626-2	Zfish	PMID:29203238
Biological Process	GO:0048793	pronephros development	epor	IMP	ZFIN:ZDB-MRPHLNO-080325-2	Zfish	PMID:29203238
Biological Process	GO:0001666	response to hypoxia	Epor	IEP		Rat	PMID:21624288|RGD:11041655
Biological Process	GO:0007165	signal transduction	Epor	IDA		Mouse	PMID:17300687

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern