Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Erbb2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ERBB2
- Mouse genes Erbb2
- Rat genes Erbb2
- Zfish genes erbb2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erbb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043125	ErbB-3 class receptor binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:12000754
Molecular Function	GO:0019838	growth factor binding	ERBB2	IDA		Human	PMID:7514177
Molecular Function	GO:0051879	Hsp90 protein binding	Erbb2	IPI	RGD:631409	Rat	PMID:15671027\|RGD:1582106
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:12000754
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:16843263
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:17148612
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:19650109
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:21203579
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:21255571
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:21480528
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:22733765
Molecular Function	GO:0042802	identical protein binding	ERBB2	IPI	UniProtKB:P04626	Human	PMID:23436906
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:10572067
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:10572067
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15303	Human	PMID:10572067
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O00750	Human	PMID:10805725
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P12931	Human	PMID:11940572
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P40763	Human	PMID:11940572
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q14451	Human	PMID:12061724
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P42679	Human	PMID:12122014
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q14451	Human	PMID:12975581
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q96JA1	Human	PMID:15282549
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q96JA1	Human	PMID:15345710
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q96EY1-1	Human	PMID:15520177
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q96EY1-2	Human	PMID:15520177
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:15657067
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15262	Human	PMID:15899872
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O00213	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O00459	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O15524	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O43639	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O75791	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O75815	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00519	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P09769	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P16885	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P19174	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P20936	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P23458	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P27986	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P29353	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P35568	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P40763	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P42224	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P42679	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P42684	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P43405	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P46109	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P52735	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P62993	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P98077	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q06124	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q08881	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q13387	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q14451	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q63HR2	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q68CZ2	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q7KZ85	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q7Z7G1	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q8TEW6	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q92529	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q92569	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q92625	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q96D37	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q99704	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9H6Q3	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9NP31	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9NSE2	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9UQF2	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9Y490	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O14980	Human	PMID:16314522
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P49792	Human	PMID:16314522
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q14974	Human	PMID:16314522
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15075	Human	PMID:16314522
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:16516204
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15303	Human	PMID:16767099
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:16843263
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:16843263
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P27986	Human	PMID:16843263
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P29353	Human	PMID:16843263
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:17148612
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:17148612
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:17426253
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q13882	Human	PMID:18719096
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P08575	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P23467	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q05209	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q12913	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15262	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q16827	Human	PMID:19167335
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P12931	Human	PMID:19372587
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P40763	Human	PMID:19372587
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:19411071
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:19650109
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q93034	Human	PMID:19933325
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O75131	Human	PMID:20010870
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:20227043
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:20558745
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P08238	Human	PMID:20650008
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q13882	Human	PMID:20700126
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P40763	Human	PMID:20876300
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P12931	Human	PMID:21075308
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:21075308
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P27986	Human	PMID:21075308
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:21203579
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:21203579
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15303	Human	PMID:21203579
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O95980	Human	PMID:21255571
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:21278786
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:21278786
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P62993	Human	PMID:21278786
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q05209	Human	PMID:21376233
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O95602	Human	PMID:21555369
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P60709	Human	PMID:21555369
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P46940	Human	PMID:21724847
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9Y316	Human	PMID:21840311
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P98172	Human	PMID:22279592
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O75367	Human	PMID:22589551
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O75367-3	Human	PMID:22589551
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:22733765
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:22806884
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:23436906
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:23436906
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:23680147
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:23688700
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q96JA1	Human	PMID:23723069
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:23866081
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:23995768
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P14625	Human	PMID:23995768
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P08238	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P11021	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P62993	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q16543	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9UJM3	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P20936	Human	PMID:24412244
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:24557338
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:24557338
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15303	Human	PMID:24557338
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P62993	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P06241	Human	PMID:24815698
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P31948	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q16543	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9HB71	Human	PMID:25036637
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q99952	Human	PMID:25081058
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q99952-1	Human	PMID:25081058
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O75791	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P00533	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P16885	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P42224	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:25326665
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9UJM3	Human	PMID:25640309
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:26517842
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P08238	Human	PMID:26517842
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P29353	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q06124	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15256	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P11021	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P31948	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9HB71	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9UQF2	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O00459	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:O14980	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P07900	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P08238	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P11021	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P27986	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P29353	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P62993	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q15303	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q16543	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q92569	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q9UJM3	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P21860	Human	PMID:7592681
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q02297-7	Human	PMID:7592681
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:Q14451	Human	PMID:9079677
Molecular Function	GO:0005515	protein binding	ERBB2	IPI	UniProtKB:P15309	Human	PMID:9705354
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	UniProtKB:Q61526	Mouse	MGI:MGI:4888096\|PMID:20639901
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	UniProtKB:P49615\|UniProtKB:P61809	Mouse	MGI:MGI:3688080\|PMID:11276227
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	UniProtKB:P18762	Mouse	MGI:MGI:3692822\|PMID:17043217
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	UniProtKB:P42227	Mouse	MGI:MGI:5437426\|PMID:20876300
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	UniProtKB:O70624	Mouse	MGI:MGI:5527213\|PMID:23897819
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	PR:Q80TH2	Mouse	PMID:10878805
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	MGI:MGI:2444417	Mouse	PMID:23553667
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	RGD:621331	Rat	PMID:15499570\|RGD:1582108
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	RGD:619758	Rat	PMID:9271418\|RGD:1582133
Molecular Function	GO:0005515	protein binding	Erbb2	IPI	RGD:620446	Rat	PMID:9271418\|RGD:1582133
Molecular Function	GO:0046982	protein heterodimerization activity	ERBB2	IPI	UniProtKB:P21860	Human	PMID:7556068
Molecular Function	GO:0004713	protein tyrosine kinase activity	ERBB2	IDA		Human	PMID:12000754
Molecular Function	GO:0004713	protein tyrosine kinase activity	ERBB2	IDA		Human	PMID:7556068
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IGI	MGI:MGI:95294	Mouse	PMID:16357442
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IGI	MGI:MGI:96070	Mouse	PMID:12621152
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IDA		Mouse	PMID:9556621
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IDA		Mouse	PMID:8702723
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IDA		Mouse	PMID:9742126
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IDA		Mouse	PMID:18701712
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IDA		Mouse	PMID:21897861
Molecular Function	GO:0004713	protein tyrosine kinase activity	Erbb2	IDA		Rat	PMID:1359541\|RGD:1582128
Molecular Function	GO:0044877	protein-containing complex binding	Erbb2	IPI	RGD:736142	Rat	PMID:16168116\|RGD:1582137
Molecular Function	GO:0044877	protein-containing complex binding	Erbb2	IPI	RGD:2543	Rat	PMID:16769812\|RGD:5131527
Molecular Function	GO:0001042	RNA polymerase I core binding	ERBB2	IDA		Human	PMID:21555369
Molecular Function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	ERBB2	IDA		Human	PMID:7514177
Molecular Function	GO:0004888	transmembrane signaling receptor activity	ERBB2	IDA		Human	PMID:7514177
Molecular Function	GO:0031625	ubiquitin protein ligase binding	Erbb2	IPI	RGD:1306167	Rat	PMID:15671027\|RGD:1582106
Cellular Component	GO:0016324	apical plasma membrane	Erbb2	IDA		Mouse	PMID:15306553
Cellular Component	GO:0016324	apical plasma membrane	Erbb2	IDA		Rat	PMID:15499570\|RGD:1582108
Cellular Component	GO:0009925	basal plasma membrane	Erbb2	IDA		Rat	PMID:15499570\|RGD:1582108
Cellular Component	GO:0016323	basolateral plasma membrane	ERBB2	IDA		Human	PMID:12646923
Cellular Component	GO:0016323	basolateral plasma membrane	Erbb2	IDA		Rat	PMID:15499570\|RGD:1582108
Cellular Component	GO:0005737	cytoplasm	Erbb2	IDA		Mouse	PMID:15306553
Cellular Component	GO:0031410	cytoplasmic vesicle	Erbb2	IDA		Mouse	PMID:23553667
Cellular Component	GO:0005829	cytosol	ERBB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0010008	endosome membrane	ERBB2	IDA		Human	PMID:16314522
Cellular Component	GO:0038143	ERBB3:ERBB2 complex	ERBB2	IDA		Human	PMID:12000754
Cellular Component	GO:0043219	lateral loop	Erbb2	IDA		Rat	PMID:15800203\|RGD:1582139
Cellular Component	GO:0045121	membrane raft	Erbb2	IDA		Rat	PMID:18199961\|RGD:2289939
Cellular Component	GO:0005902	microvillus	Erbb2	IDA		Rat	PMID:15800203\|RGD:1582139
Cellular Component	GO:0043209	myelin sheath	Erbb2	IDA		Mouse	PMID:15044753
Cellular Component	GO:0031594	neuromuscular junction	Erbb2	IMP		Mouse	PMID:22184199
Cellular Component	GO:0031594	neuromuscular junction	Erbb2	IDA		Mouse	PMID:22184199
Cellular Component	GO:0005654	nucleoplasm	ERBB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ERBB2	IDA		Human	PMID:16314522
Cellular Component	GO:0005634	nucleus	ERBB2	IDA		Human	PMID:21555369
Cellular Component	GO:0005634	nucleus	Erbb2	IDA		Rat	PMID:17553674\|RGD:2289954
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Erbb2	IDA		Rat	PMID:15800203\|RGD:1582139
Cellular Component	GO:0005886	plasma membrane	ERBB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ERBB2	IDA		Human	PMID:20010870
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:19029950
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:12621152
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:9556621
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:8702723
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:9742126
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:21897861
Cellular Component	GO:0005886	plasma membrane	Erbb2	IDA		Mouse	PMID:23553667
Cellular Component	GO:0045211	postsynaptic membrane	Erbb2	IDA		Rat	PMID:7589796\|RGD:2289975
Cellular Component	GO:0042734	presynaptic membrane	Erbb2	IDA		Mouse	PMID:24803543
Cellular Component	GO:0043235	receptor complex	ERBB2	IDA		Human	PMID:23382219
Cellular Component	GO:0043235	receptor complex	ERBB2	IDA		Human	PMID:7514177
Biological Process	GO:0007413	axonal fasciculation	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0055003	cardiac myofibril assembly	erbb2	IMP	ZFIN:ZDB-GENO-150422-7	Zfish	PMID:25228389
Biological Process	GO:0060973	cell migration involved in heart development	erbb2	IMP		Zfish	PMID:20978078
Biological Process	GO:0007166	cell surface receptor signaling pathway	ERBB2	IDA		Human	PMID:9685399
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	ERBB2	IMP		Human	PMID:27134172
Biological Process	GO:0071363	cellular response to growth factor stimulus	ERBB2	IDA		Human	PMID:20010870
Biological Process	GO:0001837	epithelial to mesenchymal transition	erbb2	IMP	ZFIN:ZDB-GENO-100308-7	Zfish	PMID:19911055
Biological Process	GO:0038134	ERBB2-EGFR signaling pathway	ERBB2	IDA		Human	PMID:8702723
Biological Process	GO:0038134	ERBB2-EGFR signaling pathway	Erbb2	IGI	MGI:MGI:95294	Mouse	PMID:16357442
Biological Process	GO:0038134	ERBB2-EGFR signaling pathway	Erbb2	IDA		Mouse	PMID:9556621
Biological Process	GO:0038134	ERBB2-EGFR signaling pathway	Erbb2	IDA		Mouse	PMID:8702723
Biological Process	GO:0038134	ERBB2-EGFR signaling pathway	Erbb2	IDA		Mouse	PMID:18701712
Biological Process	GO:0038134	ERBB2-EGFR signaling pathway	Erbb2	IDA		Mouse	PMID:21897861
Biological Process	GO:0038133	ERBB2-ERBB3 signaling pathway	Erbb2	IDA		Mouse	PMID:8702723
Biological Process	GO:0038133	ERBB2-ERBB3 signaling pathway	Erbb2	IDA		Mouse	PMID:9742126
Biological Process	GO:0038135	ERBB2-ERBB4 signaling pathway	Erbb2	IGI	MGI:MGI:104771	Mouse	PMID:12621152
Biological Process	GO:0038135	ERBB2-ERBB4 signaling pathway	Erbb2	IDA		Mouse	PMID:9556621
Biological Process	GO:0038135	ERBB2-ERBB4 signaling pathway	Erbb2	IDA		Rat	PMID:19632177\|RGD:11251908
Biological Process	GO:0044849	estrous cycle	Erbb2	IMP		Rat	PMID:11956173\|RGD:2290010
Biological Process	GO:0031101	fin regeneration	erbb2	IMP	ZFIN:ZDB-GENO-100802-3	Zfish	PMID:19133254
Biological Process	GO:0010001	glial cell differentiation	Erbb2	IGI	RGD:3187	Rat	PMID:12853432\|RGD:1358543
Biological Process	GO:0007507	heart development	Erbb2	IMP	MGI:MGI:2177255	Mouse	PMID:12072561
Biological Process	GO:0007507	heart development	Erbb2	IMP	MGI:MGI:1928827	Mouse	PMID:9362461
Biological Process	GO:0060347	heart trabecula formation	erbb2	IMP	ZFIN:ZDB-GENO-081217-1	Zfish	PMID:20978078
Biological Process	GO:0060347	heart trabecula formation	erbb2	IMP	ZFIN:ZDB-MRPHLNO-050512-1	Zfish	PMID:20978078
Biological Process	GO:0033080	immature T cell proliferation in thymus	Erbb2	IMP		Mouse	PMID:16230479
Biological Process	GO:0035556	intracellular signal transduction	ERBB2	IDA		Human	PMID:19372587
Biological Process	GO:0001889	liver development	Erbb2	IEP		Rat	PMID:12454858\|RGD:2289959
Biological Process	GO:0060056	mammary gland involution	Erbb2	IEP		Rat	PMID:10653587\|RGD:2290014
Biological Process	GO:0008045	motor neuron axon guidance	Erbb2	IMP	MGI:MGI:1929070	Mouse	PMID:10655525
Biological Process	GO:0042552	myelination	Erbb2	IMP	MGI:MGI:2177255	Mouse	PMID:10704452
Biological Process	GO:0042552	myelination	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:15797019
Biological Process	GO:0042552	myelination	erbb2	IMP	ZFIN:ZDB-GENO-050512-1	Zfish	PMID:15797019
Biological Process	GO:0048914	myelination of anterior lateral line nerve axons	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0048932	myelination of posterior lateral line nerve axons	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0043066	negative regulation of apoptotic process	Erbb2	IMP		Rat	PMID:12673197\|RGD:1582125
Biological Process	GO:0033088	negative regulation of immature T cell proliferation in thymus	Erbb2	IMP		Mouse	PMID:16230479
Biological Process	GO:0007399	nervous system development	Erbb2	IMP	MGI:MGI:3521860	Mouse	PMID:15496447
Biological Process	GO:0007399	nervous system development	Erbb2	IMP	MGI:MGI:1929071	Mouse	PMID:15496447
Biological Process	GO:0007399	nervous system development	Erbb2	IMP	MGI:MGI:3521857	Mouse	PMID:15496447
Biological Process	GO:0001755	neural crest cell migration	erbb2	IMP	ZFIN:ZDB-GENO-081217-1	Zfish	PMID:18599505
Biological Process	GO:0007528	neuromuscular junction development	Erbb2	IMP	MGI:MGI:1929070	Mouse	PMID:10655525
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Erbb2	IDA		Mouse	PMID:22184199
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Erbb2	IMP		Mouse	PMID:22184199
Biological Process	GO:0032285	non-myelinated axon ensheathment	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0048709	oligodendrocyte differentiation	Erbb2	IMP		Mouse	PMID:19139271
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ERBB2	IDA		Human	PMID:12000754
Biological Process	GO:0007422	peripheral nervous system development	Erbb2	IMP	MGI:MGI:1928827	Mouse	PMID:9362461
Biological Process	GO:0007422	peripheral nervous system development	Erbb2	IMP		Rat	PMID:15496447\|RGD:1358539
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	ERBB2	IDA		Human	PMID:7556068
Biological Process	GO:0045785	positive regulation of cell adhesion	ERBB2	IDA		Human	PMID:7556068
Biological Process	GO:0030307	positive regulation of cell growth	ERBB2	IMP		Human	PMID:21555369
Biological Process	GO:0008284	positive regulation of cell population proliferation	Erbb2	IMP		Rat	PMID:9271418\|RGD:1582133
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	ERBB2	IDA		Human	PMID:10572067
Biological Process	GO:0010628	positive regulation of gene expression	Erbb2	IMP		Mouse	PMID:24364879
Biological Process	GO:0043547	positive regulation of GTPase activity	Erbb2	IMP		Mouse	MGI:MGI:5297297\|PMID:22019888
Biological Process	GO:0043406	positive regulation of MAP kinase activity	ERBB2	IDA		Human	PMID:10572067
Biological Process	GO:0043410	positive regulation of MAPK cascade	Erbb2	IMP		Rat	PMID:16168116\|RGD:1582137
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	Erbb2	IMP		Rat	PMID:16168116\|RGD:1582137
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Erbb2	IMP		Mouse	MGI:MGI:5297297\|PMID:22019888
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	ERBB2	IDA		Human	PMID:20010870
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	Erbb2	IMP		Rat	PMID:12673197\|RGD:1582125
Biological Process	GO:0045943	positive regulation of transcription by RNA polymerase I	ERBB2	IMP		Human	PMID:21555369
Biological Process	GO:0045727	positive regulation of translation	ERBB2	IMP		Human	PMID:21555369
Biological Process	GO:0048919	posterior lateral line neuromast development	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0046777	protein autophosphorylation	ERBB2	IDA		Human	PMID:7556068
Biological Process	GO:0046777	protein autophosphorylation	Erbb2	IDA		Rat	PMID:1359541\|RGD:1582128
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	ERBB2	IMP		Human	PMID:16314522
Biological Process	GO:0032886	regulation of microtubule-based process	ERBB2	IDA		Human	PMID:20937854
Biological Process	GO:0048678	response to axon injury	Erbb2	IDA		Rat	PMID:15800203\|RGD:1582139
Biological Process	GO:0032570	response to progesterone	Erbb2	IEP		Rat	PMID:17459743\|RGD:2289991
Biological Process	GO:0009410	response to xenobiotic stimulus	Erbb2	IEP		Rat	PMID:18184445\|RGD:2289940
Biological Process	GO:0014044	Schwann cell development	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0014037	Schwann cell differentiation	erbb2	IMP	ZFIN:ZDB-GENO-050512-2	Zfish	PMID:16875686
Biological Process	GO:0007165	signal transduction	ERBB2	IDA		Human	PMID:10572067
Biological Process	GO:0007519	skeletal muscle tissue development	Erbb2	IEP		Rat	PMID:8846777\|RGD:2289973
Biological Process	GO:0048485	sympathetic nervous system development	Erbb2	IMP		Rat	PMID:15496447\|RGD:1358539
Biological Process	GO:0043586	tongue development	Erbb2	IEP		Rat	PMID:10908606\|RGD:2289970
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	ERBB2	IDA		Human	PMID:7514177
Biological Process	GO:0042060	wound healing	ERBB2	IDA		Human	PMID:12646923

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.