Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERC1
  • Mouse genes Erc1
  • Rat genes Erc1
  • Zfish genes erc1a,erc1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ERC1	HDA		Human	PMID:25468996
Molecular Function	GO:0030165	PDZ domain binding	Erc1	IDA		Rat	PMID:12391317|RGD:632516
Molecular Function	GO:0005515	protein binding	ERC1	IPI	UniProtKB:P20340	Human	PMID:12391317
Molecular Function	GO:0005515	protein binding	ERC1	IPI	UniProtKB:Q13136	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	ERC1	IPI	UniProtKB:Q86SQ7	Human	PMID:27224062
Molecular Function	GO:0005515	protein binding	Erc1	IPI	PR:P35279	Mouse	PMID:11929610
Molecular Function	GO:0005515	protein binding	Erc1	IPI	UniProtKB:Q9JIR4	Rat	PMID:12391317|RGD:632516
Molecular Function	GO:0005515	protein binding	Erc1	IPI	UniProtKB:Q9JIR4	Rat	PMID:16095618|RGD:8553467
Molecular Function	GO:0005515	protein binding	Erc1	IPI	UniProtKB:Q9JIR4	Rat	PMID:21241895|RGD:8554827
Molecular Function	GO:0031267	small GTPase binding	Erc1	IDA		Mouse	PMID:11929610
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Erc1	IEP		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Erc1	IDA		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Erc1	IMP		Mouse	PMID:27537483
Cellular Component	GO:0005813	centrosome	ERC1	IDA		Human	PMID:27224062
Cellular Component	GO:0036064	ciliary basal body	ERC1	IDA		Human	PMID:27224062
Cellular Component	GO:0005737	cytoplasm	ERC1	IDA		Human	PMID:15218148
Cellular Component	GO:0005737	cytoplasm	Erc1	IDA		Mouse	PMID:11929610
Cellular Component	GO:0098982	GABA-ergic synapse	Erc1	IDA		Mouse	PMID:25209271
Cellular Component	GO:0098982	GABA-ergic synapse	Erc1	IMP		Mouse	PMID:25209271
Cellular Component	GO:0098978	glutamatergic synapse	Erc1	IDA		Mouse	PMID:27253063
Cellular Component	GO:0098978	glutamatergic synapse	Erc1	IMP		Mouse	PMID:27253063
Cellular Component	GO:0008385	IkappaB kinase complex	ERC1	IDA		Human	PMID:15218148
Cellular Component	GO:0016020	membrane	Erc1	IDA		Rat	PMID:27626661|RGD:13601985
Cellular Component	GO:0014069	postsynaptic density	Erc1	IDA		Rat	PMID:27626661|RGD:13601985
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Erc1	IDA		Rat	PMID:12391317|RGD:632516
Cellular Component	GO:0099523	presynaptic cytosol	Erc1	IDA		Mouse	PMID:32521280
Cellular Component	GO:0045202	synapse	Erc1	IDA		Mouse	PMID:23791195
Cellular Component	GO:0008021	synaptic vesicle	Erc1	IDA		Rat	PMID:27626661|RGD:13601985
Biological Process	GO:0007252	I-kappaB phosphorylation	ERC1	IDA		Human	PMID:15218148
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	ERC1	IDA		Human	PMID:15218148
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	Erc1	IDA		Mouse	PMID:25209271
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	Erc1	IMP		Mouse	PMID:25209271
Biological Process	GO:0006355	regulation of DNA-templated transcription	ERC1	IDA		Human	PMID:15218148
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Erc1	IDA		Mouse	PMID:25209271
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Erc1	IMP		Mouse	PMID:25209271
Biological Process	GO:0042147	retrograde transport, endosome to Golgi	Erc1	IDA		Mouse	PMID:11929610
Biological Process	GO:0016082	synaptic vesicle priming	Erc1	IDA		Mouse	PMID:27253063
Biological Process	GO:0016082	synaptic vesicle priming	Erc1	IMP		Mouse	PMID:27253063

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern