Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERC2
  • Mouse genes Erc2
  • Rat genes Erc2
  • Zfish genes erc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	Erc2	IPI	RGD:620000	Rat	PMID:12163476|RGD:1299401
Molecular Function	GO:0005515	protein binding	ERC2	IPI	UniProtKB:O75145	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	ERC2	IPI	UniProtKB:O75334	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	ERC2	IPI	UniProtKB:O75335	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	ERC2	IPI	UniProtKB:Q13136	Human	PMID:12923177
Molecular Function	GO:0005515	protein binding	ERC2	IPI	UniProtKB:P10242	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	Erc2	IPI	PR:Q8BSS9	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Erc2	IPI	MGI:MGI:1924750	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Erc2	IPI	PR:B8QI36	Mouse	PMID:23791195
Molecular Function	GO:0005515	protein binding	Erc2	IPI	RGD:2223	Rat	PMID:12163476|RGD:1299401
Molecular Function	GO:0005515	protein binding	Erc2	IPI	UniProtKB:Q9JIR4	Rat	PMID:12163476|RGD:1299401
Molecular Function	GO:0044877	protein-containing complex binding	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Erc2	IDA		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Erc2	IEP		Mouse	PMID:27537483
Molecular Function	GO:0098882	structural constituent of presynaptic active zone	Erc2	IMP		Mouse	PMID:27537483
Cellular Component	GO:0098982	GABA-ergic synapse	Erc2	IDA		Mouse	PMID:19874790
Cellular Component	GO:0098982	GABA-ergic synapse	Erc2	IMP		Mouse	PMID:19874790
Cellular Component	GO:0098982	GABA-ergic synapse	Erc2	IDA		Mouse	PMID:25209271
Cellular Component	GO:0098982	GABA-ergic synapse	Erc2	IMP		Mouse	PMID:25209271
Cellular Component	GO:0098978	glutamatergic synapse	Erc2	IDA		Mouse	PMID:29439199
Cellular Component	GO:0098978	glutamatergic synapse	Erc2	IDA		Mouse	PMID:27253063
Cellular Component	GO:0098978	glutamatergic synapse	Erc2	IMP		Mouse	PMID:27253063
Cellular Component	GO:0005798	Golgi-associated vesicle	Erc2	IDA		Rat	PMID:22875941|RGD:14390063
Cellular Component	GO:0030426	growth cone	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Cellular Component	GO:0016020	membrane	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Cellular Component	GO:0043025	neuronal cell body	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Cellular Component	GO:0014069	postsynaptic density	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Cellular Component	GO:0048786	presynaptic active zone	Erc2	IDA		Rat	PMID:22875941|RGD:14390063
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Erc2	IDA		Mouse	PMID:29439199
Cellular Component	GO:0098831	presynaptic active zone cytoplasmic component	Erc2	IDA		Rat	PMID:12391317|RGD:632516
Cellular Component	GO:0042734	presynaptic membrane	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Cellular Component	GO:0032991	protein-containing complex	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Cellular Component	GO:0045202	synapse	Erc2	IDA		Mouse	PMID:23791195
Cellular Component	GO:0043195	terminal bouton	Erc2	IDA		Rat	PMID:12163476|RGD:1299401
Biological Process	GO:0048790	maintenance of presynaptic active zone structure	Erc2	IDA		Mouse	MGI:MGI:6189473|PMID:27537483
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	Erc2	IMP		Mouse	PMID:25209271
Biological Process	GO:0150037	regulation of calcium-dependent activation of synaptic vesicle fusion	Erc2	IDA		Mouse	PMID:25209271
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Erc2	IDA		Mouse	PMID:25209271
Biological Process	GO:0099509	regulation of presynaptic cytosolic calcium ion concentration	Erc2	IMP		Mouse	PMID:25209271
Biological Process	GO:0050808	synapse organization	Erc2	IEP		Rat	PMID:12163476|RGD:1299401
Biological Process	GO:0016082	synaptic vesicle priming	Erc2	IDA		Mouse	PMID:19874790
Biological Process	GO:0016082	synaptic vesicle priming	Erc2	IMP		Mouse	PMID:19874790
Biological Process	GO:0016082	synaptic vesicle priming	Erc2	IMP		Mouse	PMID:27253063
Biological Process	GO:0016082	synaptic vesicle priming	Erc2	IDA		Mouse	PMID:27253063

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern