Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERCC3
  • Mouse genes Ercc3
  • Rat genes Ercc3
  • Zfish genes ercc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ercc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043138	3'-5' DNA helicase activity	ERCC3	IDA		Human	PMID:17466626
Molecular Function	GO:0043138	3'-5' DNA helicase activity	ERCC3	IMP		Human	PMID:8663148
Molecular Function	GO:0016887	ATP hydrolysis activity	ERCC3	IDA		Human	PMID:17466626
Molecular Function	GO:0016887	ATP hydrolysis activity	Ercc3	IMP		Mouse	PMID:23562818
Molecular Function	GO:1990841	promoter-specific chromatin binding	Ercc3	IDA		Mouse	PMID:22323595
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P54727	Human	PMID:10734143
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q01831	Human	PMID:10734143
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P51948	Human	PMID:10801852
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P18074	Human	PMID:16669699
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q6ZYL4	Human	PMID:16669699
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P61201	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q92759	Human	PMID:17466626
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q6ZYL4	Human	PMID:19172752
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P18074	Human	PMID:19934020
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:O00505	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P98170	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q8NHQ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q6ZYL4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P18074	Human	PMID:27193682
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q6ZYL4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P14373	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P98170	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:O00505	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P51114-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q13573	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q14142	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q8TAP6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q9H2G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q9HAT0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q9Y5V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P04637	Human	PMID:7663514
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P29083	Human	PMID:7926747
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P29084	Human	PMID:7926747
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P18074	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P28715	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P32780	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q13888	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:Q13889	Human	PMID:8652557
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P51948	Human	PMID:8692842
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P62195	Human	PMID:9173976
Molecular Function	GO:0005515	protein binding	ERCC3	IPI	UniProtKB:P62196	Human	PMID:9173976
Cellular Component	GO:0005654	nucleoplasm	ERCC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Ercc3	IDA		Rat	PMID:18543291|RGD:9590336
Cellular Component	GO:0005669	transcription factor TFIID complex	ERCC3	IDA		Human	PMID:27193682
Cellular Component	GO:0000439	transcription factor TFIIH core complex	ERCC3	IDA		Human	PMID:8692841
Cellular Component	GO:0000439	transcription factor TFIIH core complex	ERCC3	IDA		Human	PMID:8692842
Cellular Component	GO:0000439	transcription factor TFIIH core complex	Ercc3	IDA		Rat	PMID:8855220|RGD:1642642
Cellular Component	GO:0005675	transcription factor TFIIH holo complex	ERCC3	IDA		Human	PMID:9852112
Biological Process	GO:0006915	apoptotic process	ERCC3	IMP		Human	PMID:8675009
Biological Process	GO:0006281	DNA repair	ERCC3	IMP		Human	PMID:2167179
Biological Process	GO:0006265	DNA topological change	ERCC3	IMP		Human	PMID:8663148
Biological Process	GO:0048568	embryonic organ development	Ercc3	IEP		Rat	PMID:11425516|RGD:2313673
Biological Process	GO:0035315	hair cell differentiation	ERCC3	IMP		Human	PMID:11335038
Biological Process	GO:0006289	nucleotide-excision repair	ERCC3	IMP		Human	PMID:17466626
Biological Process	GO:0006289	nucleotide-excision repair	ERCC3	IMP		Human	PMID:17509950
Biological Process	GO:0006289	nucleotide-excision repair	ERCC3	IMP		Human	PMID:8692841
Biological Process	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	ERCC3	IMP		Human	PMID:17466626
Biological Process	GO:0043065	positive regulation of apoptotic process	ERCC3	IDA		Human	PMID:16914395
Biological Process	GO:0008104	protein localization	ERCC3	IMP		Human	PMID:17509950
Biological Process	GO:1901990	regulation of mitotic cell cycle phase transition	ERCC3	IMP		Human	PMID:17088560
Biological Process	GO:0001666	response to hypoxia	Ercc3	IEP		Rat	PMID:9763211|RGD:2302855
Biological Process	GO:0006979	response to oxidative stress	ERCC3	IMP		Human	PMID:17614221
Biological Process	GO:0009411	response to UV	ERCC3	IMP		Human	PMID:17509950
Biological Process	GO:0006366	transcription by RNA polymerase II	ERCC3	IMP		Human	PMID:8663148
Biological Process	GO:0006366	transcription by RNA polymerase II	ERCC3	IDA		Human	PMID:8692841
Biological Process	GO:0006366	transcription by RNA polymerase II	ERCC3	IDA		Human	PMID:9852112
Biological Process	GO:0006362	transcription elongation by RNA polymerase I	Ercc3	EXP		Mouse	PMID:23562818
Biological Process	GO:0006283	transcription-coupled nucleotide-excision repair	ERCC3	IDA		Human	PMID:8663148
Biological Process	GO:0009650	UV protection	Ercc3	IGI	UniProtKB:A0MQ57	Mouse	PMID:1747940

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern