Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERG
  • Mouse genes Erg
  • Rat genes Erg
  • Zfish genes erg
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Erg	IDA		Mouse	PMID:22932696
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ERG	IMP		Human	PMID:18195090
Molecular Function	GO:0005515	protein binding	ERG	IPI	UniProtKB:P10275	Human	PMID:20478527
Molecular Function	GO:0005515	protein binding	ERG	IPI	UniProtKB:P09874	Human	PMID:21575865
Molecular Function	GO:0005515	protein binding	ERG	IPI	UniProtKB:P10275	Human	PMID:22531786
Molecular Function	GO:0005515	protein binding	ERG	IPI	UniProtKB:P10275	Human	PMID:22722839
Molecular Function	GO:0005515	protein binding	ERG	IPI	UniProtKB:O75164	Human	PMID:27109047
Molecular Function	GO:0005515	protein binding	Erg	IPI	UniProtKB:O88974	Mouse	MGI:MGI:3688032|PMID:11791185
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ERG	IDA		Human	PMID:23093599
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ERG	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	ERG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ERG	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Erg	IDA		Mouse	PMID:28811219
Cellular Component	GO:1990904	ribonucleoprotein complex	ERG	IDA		Human	PMID:17289661
Biological Process	GO:0001525	angiogenesis	erg	IGI	ZFIN:ZDB-MRPHLNO-060407-2,ZFIN:ZDB-MRPHLNO-090424-4	Zfish	PMID:19027849
Biological Process	GO:0001525	angiogenesis	erg	IMP	ZFIN:ZDB-MRPHLNO-090602-4	Zfish	PMID:18832752
Biological Process	GO:0001525	angiogenesis	erg	IGI	ZFIN:ZDB-MRPHLNO-081231-1,ZFIN:ZDB-MRPHLNO-090602-4	Zfish	PMID:18832752
Biological Process	GO:0060217	hemangioblast cell differentiation	erg	IDA		Zfish	PMID:19027849
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ERG	IDA		Human	PMID:18195090
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ERG	IMP		Human	PMID:18195090
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ERG	IMP		Human	PMID:22235125
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ERG	IDA		Human	PMID:23913826

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern