Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERLIN1
  • Mouse genes Erlin1
  • Rat genes Erlin1
  • Zfish genes erlin1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Erlin1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015485	cholesterol binding	ERLIN1	IDA		Human	PMID:24217618
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:O94905	Human	PMID:19240031
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:O94905	Human	PMID:21343306
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q86TM6	Human	PMID:21343306
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q9UKV5	Human	PMID:21343306
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:O94905	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q86TM6	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q9UKV5	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:B2RDE6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q8N511	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q8TD06	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q96IW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:O94905	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q15436	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q7L5A8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q8N0V3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q8TD06	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERLIN1	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Cellular Component	GO:0005783	endoplasmic reticulum	ERLIN1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ERLIN1	IDA		Human	PMID:16835267
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ERLIN1	IDA		Human	PMID:19240031
Cellular Component	GO:0032991	protein-containing complex	ERLIN1	IDA		Human	PMID:18468998
Biological Process	GO:0045541	negative regulation of cholesterol biosynthetic process	ERLIN1	IMP		Human	PMID:24217618
Biological Process	GO:0045717	negative regulation of fatty acid biosynthetic process	ERLIN1	IMP		Human	PMID:24217618
Biological Process	GO:0045540	regulation of cholesterol biosynthetic process	ERLIN1	IDA		Human	PMID:24217618
Biological Process	GO:0032933	SREBP signaling pathway	ERLIN1	IMP		Human	PMID:24217618
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	ERLIN1	IDA		Human	PMID:19240031

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern