Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERO1B
  • Mouse genes Ero1b
  • Rat genes Ero1b
  • Zfish genes ero1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ero1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015036	disulfide oxidoreductase activity	Ero1b	IDA		Mouse	PMID:20308425
Molecular Function	GO:0015036	disulfide oxidoreductase activity	Ero1b	IMP	MGI:MGI:3864866	Mouse	PMID:20308425
Molecular Function	GO:0005515	protein binding	ERO1B	IPI	UniProtKB:P30101	Human	PMID:20802462
Molecular Function	GO:0015035	protein-disulfide reductase activity	ERO1B	EXP		Human	PMID:11707400
Molecular Function	GO:0015035	protein-disulfide reductase activity	ERO1B	EXP		Human	PMID:16407158
Molecular Function	GO:0015035	protein-disulfide reductase activity	ERO1B	EXP		Human	PMID:21091435
Molecular Function	GO:0015035	protein-disulfide reductase activity	Ero1b	IDA		Mouse	PMID:20308425
Molecular Function	GO:0016972	thiol oxidase activity	ERO1B	IDA		Human	PMID:21091435
Cellular Component	GO:0005788	endoplasmic reticulum lumen	Ero1b	IDA		Mouse	PMID:20308425
Cellular Component	GO:0016020	membrane	Ero1b	IDA		Mouse	PMID:20308425
Biological Process	GO:0045454	cell redox homeostasis	Ero1b	IGI	MGI:MGI:1859815	Mouse	PMID:23589496
Biological Process	GO:0045454	cell redox homeostasis	Ero1b	IGI	MGI:MGI:1354385	Mouse	PMID:23589496
Biological Process	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	Ero1b	IMP	MGI:MGI:5504624	Mouse	PMID:31184304
Biological Process	GO:0030198	extracellular matrix organization	Ero1b	IGI	MGI:MGI:1859815	Mouse	PMID:22981861
Biological Process	GO:0030198	extracellular matrix organization	Ero1b	IGI	MGI:MGI:1354385	Mouse	PMID:22981861
Biological Process	GO:0042593	glucose homeostasis	Ero1b	IMP	MGI:MGI:3864866	Mouse	PMID:20308425
Biological Process	GO:0030070	insulin processing	Ero1b	IMP	MGI:MGI:3864866	Mouse	PMID:20308425
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Ero1b	IGI	MGI:MGI:1354385	Mouse	PMID:22981861
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Ero1b	IGI	MGI:MGI:1859815	Mouse	PMID:22981861
Biological Process	GO:0034975	protein folding in endoplasmic reticulum	ERO1B	IDA		Human	PMID:21091435
Biological Process	GO:0022417	protein maturation by protein folding	Ero1b	IMP	MGI:MGI:3864866	Mouse	PMID:20308425
Biological Process	GO:0022417	protein maturation by protein folding	Ero1b	IGI	MGI:MGI:1859815	Mouse	PMID:22981861
Biological Process	GO:0022417	protein maturation by protein folding	Ero1b	IGI	MGI:MGI:1354385	Mouse	PMID:22981861

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern