Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ERRFI1
  • Mouse genes Errfi1
  • Rat genes Errfi1
  • Zfish genes errfi1a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Errfi1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019900	kinase binding	Errfi1	IPI	UniProtKB:P00533	Rat	PMID:17599051|RGD:8553726
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P31947	Human	PMID:15778465
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P00533	Human	PMID:18046415
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P00533	Human	PMID:18776048
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:21706016
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:O14757	Human	PMID:22505024
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P00533	Human	PMID:23273428
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P00533	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P04626	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:24189400
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P04626	Human	PMID:25640309
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P06241-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P62993	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ERRFI1	IPI	UniProtKB:P04626	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Errfi1	IPI	UniProtKB:Q60631	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Errfi1	IPI	RGD:11498	Rat	PMID:10749885|RGD:9685546
Molecular Function	GO:0005515	protein binding	Errfi1	IPI	RGD:10533	Rat	PMID:11003669|RGD:9685556
Molecular Function	GO:0019901	protein kinase binding	ERRFI1	IPI	UniProtKB:P00533	Human	PMID:18046415
Molecular Function	GO:0017124	SH3 domain binding	Errfi1	IDA		Rat	PMID:11003669|RGD:9685556
Molecular Function	GO:0031267	small GTPase binding	Errfi1	IPI	RGD:730976	Rat	PMID:10749885|RGD:9685546
Cellular Component	GO:0005737	cytoplasm	Errfi1	IDA		Mouse	MGI:MGI:3629275|PMID:16648858
Cellular Component	GO:0005829	cytosol	ERRFI1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Errfi1	IDA		Rat	PMID:11003669|RGD:9685556
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	Errfi1	IDA		Mouse	MGI:MGI:3629275|PMID:16648858
Cellular Component	GO:0005886	plasma membrane	Errfi1	IDA		Rat	PMID:11003669|RGD:9685556
Biological Process	GO:0071474	cellular hyperosmotic response	Errfi1	IEP		Rat	PMID:10749885|RGD:9685546
Biological Process	GO:0071549	cellular response to dexamethasone stimulus	Errfi1	IEP		Rat	PMID:23384834|RGD:9685543
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	Errfi1	IEP		Rat	PMID:15556944|RGD:9685545
Biological Process	GO:0032869	cellular response to insulin stimulus	Errfi1	IEP		Rat	PMID:15358516|RGD:9685544
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Errfi1	IEP		Rat	PMID:15556944|RGD:9685545
Biological Process	GO:0048286	lung alveolus development	Errfi1	IMP		Mouse	MGI:MGI:4366137|PMID:19710174
Biological Process	GO:0060428	lung epithelium development	Errfi1	IMP		Mouse	MGI:MGI:4366137|PMID:19710174
Biological Process	GO:0060426	lung vasculature development	Errfi1	IMP		Mouse	MGI:MGI:4366137|PMID:19710174
Biological Process	GO:1903243	negative regulation of cardiac muscle hypertrophy in response to stress	Errfi1	IDA		Rat	PMID:19204184|RGD:9685562
Biological Process	GO:0032966	negative regulation of collagen biosynthetic process	Errfi1	IMP		Rat	PMID:19204184|RGD:9685562
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	Errfi1	IMP		Mouse	MGI:MGI:4366137|PMID:19710174
Biological Process	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	Errfi1	IMP		Rat	PMID:19204184|RGD:9685562
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	ERRFI1	IDA		Human	PMID:18046415
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	Errfi1	IMP		Mouse	MGI:MGI:3629275|PMID:16648858
Biological Process	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity	Errfi1	IDA		Rat	PMID:17599051|RGD:8553726
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	Errfi1	IDA		Rat	PMID:19204184|RGD:9685562
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	Errfi1	IMP		Rat	PMID:19204184|RGD:9685562
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	Errfi1	IDA		Rat	PMID:17599051|RGD:8553726
Biological Process	GO:0031953	negative regulation of protein autophosphorylation	ERRFI1	IDA		Human	PMID:18046415
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Errfi1	IMP		Rat	PMID:19204184|RGD:9685562
Biological Process	GO:0045616	regulation of keratinocyte differentiation	Errfi1	IMP		Mouse	MGI:MGI:3629275|PMID:16648858
Biological Process	GO:0061469	regulation of type B pancreatic cell proliferation	Errfi1	IMP		Rat	PMID:23384834|RGD:9685543
Biological Process	GO:0043589	skin morphogenesis	Errfi1	IMP		Mouse	MGI:MGI:3629275|PMID:16648858

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern