Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ESPL1
  • Mouse genes Espl1
  • Rat genes Espl1
  • Zfish genes espl1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Espl1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008234	cysteine-type peptidase activity	Espl1	IDA		Mouse	PMID:23975099
Molecular Function	GO:0008233	peptidase activity	Espl1	IDA		Mouse	PMID:19625504
Molecular Function	GO:0005515	protein binding	ESPL1	IPI	UniProtKB:O95997	Human	PMID:12194817
Molecular Function	GO:0005515	protein binding	ESPL1	IPI	UniProtKB:O60216	Human	PMID:12672959
Cellular Component	GO:0005813	centrosome	ESPL1	IDA		Human	PMID:12672959
Biological Process	GO:0007059	chromosome segregation	Espl1	IGI	MGI:MGI:1353578	Mouse	PMID:16533945
Biological Process	GO:0045143	homologous chromosome segregation	Espl1	IMP		Mouse	PMID:14561405
Biological Process	GO:0007127	meiosis I	Espl1	IMP		Mouse	PMID:14561405
Biological Process	GO:0000212	meiotic spindle organization	Espl1	IMP		Mouse	PMID:14561405
Biological Process	GO:0000278	mitotic cell cycle	Espl1	IGI	MGI:MGI:2675859	Mouse	PMID:23975099
Biological Process	GO:0000070	mitotic sister chromatid segregation	ESPL1	IMP		Human	PMID:12672959
Biological Process	GO:0000070	mitotic sister chromatid segregation	Espl1	IMP	MGI:MGI:3624200	Mouse	PMID:16533945

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern