Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ESYT2
  • Mouse genes Esyt2
  • Rat genes Esyt2
  • Zfish genes esyt2a,esyt2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Esyt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	ESYT2	HDA		Human	PMID:25468996
Molecular Function	GO:0005509	calcium ion binding	ESYT2	IDA		Human	PMID:24373768
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	ESYT2	IDA		Human	PMID:17360437
Molecular Function	GO:0042802	identical protein binding	ESYT2	IPI	UniProtKB:A0FGR8	Human	PMID:23791178
Molecular Function	GO:0042802	identical protein binding	ESYT2	IPI	UniProtKB:A0FGR8	Human	PMID:24847877
Molecular Function	GO:0031210	phosphatidylcholine binding	ESYT2	IDA		Human	PMID:24847877
Molecular Function	GO:0008429	phosphatidylethanolamine binding	ESYT2	IDA		Human	PMID:24847877
Molecular Function	GO:0035091	phosphatidylinositol binding	ESYT2	IDA		Human	PMID:24847877
Molecular Function	GO:0005515	protein binding	ESYT2	IPI	UniProtKB:Q9BSJ8	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	ESYT2	IPI	UniProtKB:A0FGR9	Human	PMID:23791178
Molecular Function	GO:0005515	protein binding	ESYT2	IPI	UniProtKB:Q9BSJ8	Human	PMID:23791178
Molecular Function	GO:0005515	protein binding	ESYT2	IPI	UniProtKB:A0FGR9	Human	PMID:27065097
Molecular Function	GO:0005515	protein binding	ESYT2	IPI	UniProtKB:Q9BSJ8	Human	PMID:27065097
Cellular Component	GO:0005829	cytosol	ESYT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ESYT2	IDA		Human	PMID:23791178
Cellular Component	GO:0140268	endoplasmic reticulum-plasma membrane contact site	ESYT2	IDA		Human	PMID:27044890
Cellular Component	GO:0140268	endoplasmic reticulum-plasma membrane contact site	ESYT2	IDA		Human	PMID:30220461
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	ESYT2	IMP		Human	PMID:23791178
Cellular Component	GO:0016020	membrane	ESYT2	HDA		Human	PMID:19946888
Cellular Component	GO:0044232	organelle membrane contact site	ESYT2	IDA		Human	PMID:23791178
Cellular Component	GO:0005886	plasma membrane	ESYT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ESYT2	IDA		Human	PMID:17360437

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern