Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ets1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ETS1
- Mouse genes Ets1
- Rat genes Ets1
- Zfish genes ets1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ets1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Ets1	IDA		Mouse	MGI:MGI:3690807\|PMID:7774816
Molecular Function	GO:0003677	DNA binding	Ets1	IDA		Mouse	PMID:12119294
Molecular Function	GO:0003677	DNA binding	Ets1	IDA		Mouse	PMID:15541767
Molecular Function	GO:0003677	DNA binding	ets1	IDA		Zfish	PMID:15893977
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ETS1	IDA		Human	PMID:15001984
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ETS1	IDA		Human	PMID:10698492
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ETS1	IDA		Human	PMID:11909962
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ETS1	IDA		Human	PMID:15247905
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Ets1	IDA		Mouse	PMID:12119294
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ets1	IMP		Zfish	PMID:15893977
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	ETS1	IDA		Human	PMID:21711453
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Ets1	IPI	UniProtKB:Q01196-11\|UniProtKB:Q01196-1	Mouse	MGI:MGI:3715067\|PMID:9199349
Molecular Function	GO:0035035	histone acetyltransferase binding	Ets1	IPI	RGD:620036	Rat	PMID:22357921\|RGD:7257571
Molecular Function	GO:0042802	identical protein binding	ETS1	IPI	UniProtKB:P14921	Human	PMID:25609649
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ETS1	IMP		Human	PMID:31146003
Molecular Function	GO:0003676	nucleic acid binding	ETS1	EXP		Human	PMID:25083921
Molecular Function	GO:0003676	nucleic acid binding	Ets1	EXP		Mouse	MGI:MGI:5882895\|PMID:15994560
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:Q9UER7	Human	PMID:10698492
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:P23497	Human	PMID:15247905
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:P70338	Human	PMID:17213822
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:O00470	Human	PMID:18692240
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:O60841	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:P05412	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:Q05519	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:Q06481	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:Q4LE39	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:Q9BQA9	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:P17542	Human	PMID:21179004
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:P78527	Human	PMID:21575865
Molecular Function	GO:0005515	protein binding	ETS1	IPI	UniProtKB:Q05519	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	Ets1	IPI	UniProtKB:P16951\|UniProtKB:Q03347	Mouse	MGI:MGI:3690807\|PMID:7774816
Molecular Function	GO:0005515	protein binding	Ets1	IPI	UniProtKB:P45481	Mouse	MGI:MGI:5919489\|PMID:20534573
Molecular Function	GO:0005515	protein binding	Ets1	IPI	UniProtKB:O43711\|UniProtKB:P31314	Mouse	MGI:MGI:5431184\|PMID:22516263
Molecular Function	GO:0005515	protein binding	Ets1	IPI	RGD:2741	Rat	PMID:12145332\|RGD:2313690
Molecular Function	GO:0005515	protein binding	Ets1	IPI	RGD:3738	Rat	PMID:15297375\|RGD:2313716
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ETS1	IDA		Human	PMID:12119294
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ETS1	IPI	UniProtKB:P23497-1	Human	PMID:11909962
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ETS1	IPI	UniProtKB:P23497-2	Human	PMID:11909962
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ETS1	IPI	UniProtKB:P23497-3	Human	PMID:11909962
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ETS1	IPI	UniProtKB:P23497-4	Human	PMID:11909962
Molecular Function	GO:0043565	sequence-specific DNA binding	Ets1	IDA		Mouse	PMID:1409581
Molecular Function	GO:0043565	sequence-specific DNA binding	Ets1	IDA		Rat	PMID:8635216\|RGD:2313682
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	Ets1	IMP		Mouse	MGI:MGI:5882895\|PMID:15994560
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ETS1	IDA		Human	PMID:31146003
Molecular Function	GO:0001222	transcription corepressor binding	ETS1	IDA		Human	PMID:10698492
Cellular Component	GO:0005654	nucleoplasm	ETS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ETS1	IDA		Human	PMID:11909962
Cellular Component	GO:0005634	nucleus	ETS1	IDA		Human	PMID:15247905
Cellular Component	GO:0005634	nucleus	Ets1	IDA		Mouse	PMID:12119294
Cellular Component	GO:0005634	nucleus	Ets1	IDA		Rat	PMID:31932071\|RGD:150429812
Cellular Component	GO:0005634	nucleus	Ets1	IDA		Rat	PMID:9600079\|RGD:2313680
Cellular Component	GO:0005667	transcription regulator complex	Ets1	IDA		Mouse	PMID:12464608
Biological Process	GO:0060055	angiogenesis involved in wound healing	Ets1	IEP		Rat	PMID:9600079\|RGD:2313680
Biological Process	GO:0060837	blood vessel endothelial cell differentiation	ets1	IGI	ZFIN:ZDB-GENO-220714-6	Zfish	PMID:32628937
Biological Process	GO:0048514	blood vessel morphogenesis	ets1	IGI	ZFIN:ZDB-MRPHLNO-070605-4,ZFIN:ZDB-MRPHLNO-070605-5,ZFIN:ZDB-MRPHLNO-070605-6	Zfish	PMID:17125762
Biological Process	GO:0048514	blood vessel morphogenesis	ets1	IGI	ZFIN:ZDB-MRPHLNO-070605-1,ZFIN:ZDB-MRPHLNO-070605-4,ZFIN:ZDB-MRPHLNO-070605-6	Zfish	PMID:17125762
Biological Process	GO:0048514	blood vessel morphogenesis	ets1	IMP	ZFIN:ZDB-MRPHLNO-070605-4	Zfish	PMID:17125762
Biological Process	GO:0048514	blood vessel morphogenesis	ets1	IGI	ZFIN:ZDB-MRPHLNO-070605-1,ZFIN:ZDB-MRPHLNO-070605-4,ZFIN:ZDB-MRPHLNO-070605-5	Zfish	PMID:17125762
Biological Process	GO:0048870	cell motility	ETS1	IMP		Human	PMID:15247905
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Ets1	IEP		Rat	PMID:16192649\|RGD:2313718
Biological Process	GO:0006351	DNA-templated transcription	Ets1	IDA		Mouse	MGI:MGI:2387736\|PMID:12119294
Biological Process	GO:0044849	estrous cycle	Ets1	IEP		Rat	PMID:18439600\|RGD:2313729
Biological Process	GO:0007565	female pregnancy	Ets1	IEP		Rat	PMID:18439600\|RGD:2313729
Biological Process	GO:0021854	hypothalamus development	Ets1	IEP		Rat	PMID:8946059\|RGD:2313681
Biological Process	GO:0050728	negative regulation of inflammatory response	Ets1	IMP		Mouse	MGI:MGI:5619451\|PMID:22294049
Biological Process	GO:0021983	pituitary gland development	Ets1	IEP		Rat	PMID:8946059\|RGD:2313681
Biological Process	GO:0030578	PML body organization	ETS1	IDA		Human	PMID:11909962
Biological Process	GO:0030578	PML body organization	ETS1	IDA		Human	PMID:15247905
Biological Process	GO:0045766	positive regulation of angiogenesis	ETS1	IMP		Human	PMID:21081489
Biological Process	GO:0045766	positive regulation of angiogenesis	Ets1	IMP		Rat	PMID:12725417\|RGD:2313689
Biological Process	GO:0043536	positive regulation of blood vessel endothelial cell migration	ETS1	IMP		Human	PMID:21081489
Biological Process	GO:0030335	positive regulation of cell migration	Ets1	IMP		Rat	PMID:19148472\|RGD:2313726
Biological Process	GO:0008284	positive regulation of cell population proliferation	Ets1	IMP		Rat	PMID:15806297\|RGD:2313723
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ETS1	IDA		Human	PMID:10698492
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ETS1	IMP		Human	PMID:31146003
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ETS1	IMP		Human	PMID:15592518
Biological Process	GO:0045648	positive regulation of erythrocyte differentiation	ETS1	IDA		Human	PMID:8620536
Biological Process	GO:0010628	positive regulation of gene expression	ETS1	IMP		Human	PMID:21081489
Biological Process	GO:0050729	positive regulation of inflammatory response	ETS1	IDA		Human	PMID:21310411
Biological Process	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	ETS1	IMP		Human	PMID:21310411
Biological Process	GO:1902895	positive regulation of miRNA transcription	ETS1	IDA		Human	PMID:21711453
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ETS1	IDA		Human	PMID:11909962
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ETS1	IDA		Human	PMID:15001984
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ETS1	IDA		Human	PMID:15247905
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ets1	IDA		Mouse	MGI:MGI:2387736\|PMID:12119294
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ets1	IGI	MGI:MGI:109169	Mouse	PMID:12464608
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ets1	IDA		Mouse	PMID:12464608
Biological Process	GO:0045765	regulation of angiogenesis	ETS1	IMP		Human	PMID:15592518
Biological Process	GO:0006355	regulation of DNA-templated transcription	Ets1	IDA		Mouse	MGI:MGI:2387736\|PMID:12119294
Biological Process	GO:2000351	regulation of endothelial cell apoptotic process	ets1	IMP	ZFIN:ZDB-GENO-220714-4	Zfish	PMID:32628937
Biological Process	GO:2000351	regulation of endothelial cell apoptotic process	ets1	IGI	ZFIN:ZDB-GENO-220714-6	Zfish	PMID:32628937
Biological Process	GO:0010715	regulation of extracellular matrix disassembly	Ets1	IMP		Rat	PMID:16738537\|RGD:2313717
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ets1	IDA		Mouse	PMID:15541767
Biological Process	GO:0032355	response to estradiol	Ets1	IEP		Rat	PMID:12725417\|RGD:2313689
Biological Process	GO:0001666	response to hypoxia	Ets1	IEP		Rat	PMID:15579511\|RGD:2313701
Biological Process	GO:0070555	response to interleukin-1	Ets1	IEP		Rat	PMID:16046515\|RGD:2313720
Biological Process	GO:0034616	response to laminar fluid shear stress	Ets1	IEP		Rat	PMID:18636553\|RGD:2313727
Biological Process	GO:0009612	response to mechanical stimulus	Ets1	IEP		Rat	PMID:18272346\|RGD:2313730
Biological Process	GO:1902074	response to salt	Ets1	IEP		Rat	PMID:31932071\|RGD:150429812
Biological Process	GO:0009611	response to wounding	Ets1	IEP		Rat	PMID:8635216\|RGD:2313682

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.