Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ETV3
  • Mouse genes Etv3
  • Rat genes Etv3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Etv3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017151	DEAD/H-box RNA helicase binding	Etv3	IPI	UniProtKB:Q9UHI6	Mouse	MGI:MGI:2178490|PMID:12007404
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Etv3	IDA		Mouse	MGI:MGI:2178490|PMID:12007404
Molecular Function	GO:0005515	protein binding	Etv3	IPI	PR:Q9JJY4	Mouse	PMID:12007404
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Etv3	IDA		Mouse	MGI:MGI:2178490|PMID:12007404
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ETV3	IDA		Human	PMID:28473536
Cellular Component	GO:0000785	chromatin	Etv3	IDA		Mouse	MGI:MGI:2178490|PMID:12007404
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ETV3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ETV3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090571	RNA polymerase II transcription repressor complex	Etv3	IDA		Mouse	MGI:MGI:2178490|PMID:12007404
Cellular Component	GO:0017053	transcription repressor complex	Etv3	IDA		Mouse	PMID:12007404
Biological Process	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	Etv3	IDA		Mouse	MGI:MGI:2178490|PMID:12007404
Biological Process	GO:0008285	negative regulation of cell population proliferation	Etv3	IDA		Mouse	MGI:MGI:2178490|PMID:12007404
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Etv3	IDA		Mouse	PMID:12007404

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern