Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ETV5
  • Mouse genes Etv5
  • Rat genes Etv5
  • Zfish genes etv5a,etv5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Etv5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ETV5	IMP		Human	PMID:15857832
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ETV5	IDA		Human	PMID:19443906
Molecular Function	GO:0005515	protein binding	ETV5	IPI	UniProtKB:Q9UJ78	Human	PMID:17126306
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ETV5	IMP		Human	PMID:15857832
Molecular Function	GO:0043565	sequence-specific DNA binding	etv5b	IDA		Zfish	PMID:18177854
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ETV5	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ETV5	IDA		Human	PMID:19443906
Cellular Component	GO:0005654	nucleoplasm	ETV5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ETV5	IDA		Human	PMID:19443906
Biological Process	GO:0034599	cellular response to oxidative stress	ETV5	IDA		Human	PMID:19443906
Biological Process	GO:0060217	hemangioblast cell differentiation	etv5a	IMP	ZFIN:ZDB-MRPHLNO-140402-3	Zfish	PMID:24101720
Biological Process	GO:0060217	hemangioblast cell differentiation	etv5a	IMP	ZFIN:ZDB-MRPHLNO-140402-4	Zfish	PMID:24101720
Biological Process	GO:0021979	hypothalamus cell differentiation	etv5b	IMP	ZFIN:ZDB-MRPHLNO-100623-10	Zfish	PMID:23250211
Biological Process	GO:0035108	limb morphogenesis	etv5a	IGI	ZFIN:ZDB-MRPHLNO-100617-9,ZFIN:ZDB-MRPHLNO-100621-3,ZFIN:ZDB-MRPHLNO-100621-4	Zfish	PMID:19386268
Biological Process	GO:0035108	limb morphogenesis	etv5b	IGI	ZFIN:ZDB-MRPHLNO-100617-9,ZFIN:ZDB-MRPHLNO-100621-3,ZFIN:ZDB-MRPHLNO-100621-4	Zfish	PMID:19386268
Biological Process	GO:0007626	locomotory behavior	Etv5	IMP	MGI:MGI:3589421	Mouse	PMID:17785180
Biological Process	GO:0048133	male germ-line stem cell asymmetric division	Etv5	IMP		Rat	PMID:19339709|RGD:2316287
Biological Process	GO:0008045	motor neuron axon guidance	etv5b	IMP	ZFIN:ZDB-MRPHLNO-100621-3	Zfish	PMID:27273160
Biological Process	GO:0008285	negative regulation of cell population proliferation	etv5a	IMP	ZFIN:ZDB-MRPHLNO-140402-4	Zfish	PMID:24101720
Biological Process	GO:0008285	negative regulation of cell population proliferation	etv5a	IMP	ZFIN:ZDB-MRPHLNO-140402-3	Zfish	PMID:24101720
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	ETV5	IDA		Human	PMID:17126306
Biological Process	GO:0007274	neuromuscular synaptic transmission	Etv5	IMP	MGI:MGI:3589421	Mouse	PMID:17785180
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Etv5	IDA		Mouse	PMID:15466854
Biological Process	GO:0060252	positive regulation of glial cell proliferation	Etv5	IMP		Rat	PMID:12297104|RGD:2316288
Biological Process	GO:0045666	positive regulation of neuron differentiation	Etv5	IMP		Rat	PMID:12297104|RGD:2316288
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ETV5	IMP		Human	PMID:15857832
Biological Process	GO:0035778	pronephric nephron tubule epithelial cell differentiation	etv5a	IMP	ZFIN:ZDB-MRPHLNO-100621-4	Zfish	PMID:26827902
Biological Process	GO:0035778	pronephric nephron tubule epithelial cell differentiation	etv5a	IGI	ZFIN:ZDB-MRPHLNO-100617-9,ZFIN:ZDB-MRPHLNO-100621-4	Zfish	PMID:26827902
Biological Process	GO:0048793	pronephros development	etv5b	IGI	ZFIN:ZDB-MRPHLNO-080311-1,ZFIN:ZDB-MRPHLNO-080311-2	Zfish	PMID:21184241
Biological Process	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	Etv5	IDA		Mouse	PMID:12871699
Biological Process	GO:0007346	regulation of mitotic cell cycle	etv5b	IMP	ZFIN:ZDB-MRPHLNO-100623-10	Zfish	PMID:23250211
Biological Process	GO:0050807	regulation of synapse organization	Etv5	IMP	MGI:MGI:3589421	Mouse	PMID:17785180
Biological Process	GO:0071340	skeletal muscle acetylcholine-gated channel clustering	Etv5	IMP	MGI:MGI:3589421	Mouse	PMID:17785180

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern