Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC2
  • Mouse genes Exosc2
  • Rat genes Exosc2
  • Zfish genes exosc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q15024	Human	PMID:11719186
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q99547	Human	PMID:11719186
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NPD3	Human	PMID:11719186
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:11719186
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q15024	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NPD3	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q15024	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9H9D4	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:P26651	Human	PMID:15687258
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q07352	Human	PMID:15687258
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q99547	Human	PMID:16396833
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:16396833
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NPD3	Human	PMID:17545563
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:17545563
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q07352	Human	PMID:18326031
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NPD3	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q8TF46-1	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NPD3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q15024	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NPD3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q15024	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:Q9NQT5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC2	IPI	UniProtKB:P0C264	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	EXOSC2	IDA		Human	PMID:17545563
Cellular Component	GO:0005829	cytosol	EXOSC2	IDA		Human	PMID:20531386
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC2	IDA		Human	PMID:12419256
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC2	IDA		Human	PMID:20531389
Cellular Component	GO:0000176	nuclear exosome (RNase complex)	EXOSC2	IDA		Human	PMID:26166824
Cellular Component	GO:0005730	nucleolus	EXOSC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	EXOSC2	IDA		Human	PMID:20531386
Cellular Component	GO:0005654	nucleoplasm	EXOSC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EXOSC2	IDA		Human	PMID:17545563
Cellular Component	GO:0005634	nucleus	EXOSC2	IDA		Human	PMID:20531386
Biological Process	GO:0003407	neural retina development	exosc2	IMP	ZFIN:ZDB-GENO-220520-1	Zfish	PMID:33333712
Biological Process	GO:0030307	positive regulation of cell growth	EXOSC2	IMP		Human	PMID:17545563
Biological Process	GO:0009259	ribonucleotide metabolic process	exosc2	IMP	ZFIN:ZDB-GENO-220520-1	Zfish	PMID:33333712
Biological Process	GO:0006401	RNA catabolic process	EXOSC2	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC2	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC2	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC2	IDA		Human	PMID:20531386
Biological Process	GO:0021510	spinal cord development	exosc2	IMP	ZFIN:ZDB-GENO-220520-1	Zfish	PMID:33333712

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern