Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC3
  • Mouse genes Exosc3
  • Rat genes Exosc3
  • Zfish genes exosc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:11719186
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9H2U1	Human	PMID:14731398
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q96B26	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:16396833
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8K3Y6	Human	PMID:17185417
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:17545563
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8K3Y6	Human	PMID:18334637
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q92841	Human	PMID:18334637
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8TF46	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9Y2L1	Human	PMID:20531386
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8TF46	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q96B26	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9Y2L1	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q96B26	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9Y2L1	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q7Z2W4	Human	PMID:21876179
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8TF46	Human	PMID:23756462
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8TF46	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q96B26	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q8TF46	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q13868	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q96B26	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NPD3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q9NQT4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC3	IPI	UniProtKB:Q969E8	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	EXOSC3	IDA		Human	PMID:17545563
Cellular Component	GO:0000177	cytoplasmic exosome (RNase complex)	EXOSC3	IDA		Human	PMID:11110791
Cellular Component	GO:0005829	cytosol	EXOSC3	IDA		Human	PMID:20531386
Cellular Component	GO:0000791	euchromatin	EXOSC3	IMP		Human	PMID:20699273
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC3	IDA		Human	PMID:20531389
Cellular Component	GO:0000176	nuclear exosome (RNase complex)	EXOSC3	IDA		Human	PMID:11110791
Cellular Component	GO:0005730	nucleolus	EXOSC3	IDA		Human	PMID:20531386
Cellular Component	GO:0005730	nucleolus	EXOSC3	IDA		Human	PMID:20531389
Cellular Component	GO:0005654	nucleoplasm	EXOSC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EXOSC3	IDA		Human	PMID:17545563
Cellular Component	GO:0005634	nucleus	EXOSC3	IDA		Human	PMID:20531386
Biological Process	GO:0007409	axonogenesis	exosc3	IMP	ZFIN:ZDB-MRPHLNO-120611-1	Zfish	PMID:27193168
Biological Process	GO:0007420	brain development	exosc3	IMP	ZFIN:ZDB-MRPHLNO-120612-1	Zfish	PMID:22544365
Biological Process	GO:0007420	brain development	exosc3	IMP	ZFIN:ZDB-MRPHLNO-120611-1	Zfish	PMID:22544365
Biological Process	GO:0021693	cerebellar Purkinje cell layer structural organization	exosc3	IMP	ZFIN:ZDB-MRPHLNO-120611-1	Zfish	PMID:27193168
Biological Process	GO:0043009	chordate embryonic development	exosc3	IMP	ZFIN:ZDB-MRPHLNO-120612-1	Zfish	PMID:22544365
Biological Process	GO:0043009	chordate embryonic development	exosc3	IMP	ZFIN:ZDB-MRPHLNO-120611-1	Zfish	PMID:22544365
Biological Process	GO:0071034	CUT catabolic process	EXOSC3	IMP		Human	PMID:19056938
Biological Process	GO:0045006	DNA deamination	EXOSC3	IDA		Human	PMID:21255825
Biological Process	GO:0043928	exonucleolytic catabolism of deadenylated mRNA	EXOSC3	IMP		Human	PMID:11782436
Biological Process	GO:0045190	isotype switching	Exosc3	IMP		Mouse	MGI:MGI:5009766|PMID:21255825
Biological Process	GO:0045830	positive regulation of isotype switching	Exosc3	IMP		Mouse	PMID:21255825
Biological Process	GO:0006401	RNA catabolic process	EXOSC3	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC3	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC3	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC3	IDA		Human	PMID:20531386
Biological Process	GO:0006364	rRNA processing	EXOSC3	IDA		Human	PMID:11110791

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern