Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC6
  • Mouse genes Exosc6
  • Rat genes Exosc6
  • Zfish genes exosc6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003723	RNA binding	EXOSC6	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	EXOSC6	IDA		Human	PMID:20531386
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC6	IDA		Human	PMID:20531389
Cellular Component	GO:0005730	nucleolus	EXOSC6	IDA		Human	PMID:20531386
Cellular Component	GO:0005634	nucleus	EXOSC6	IDA		Human	PMID:20531386
Biological Process	GO:0045006	DNA deamination	EXOSC6	IDA		Human	PMID:21255825
Biological Process	GO:0045190	isotype switching	Exosc6	IMP		Mouse	MGI:MGI:5009766|PMID:21255825
Biological Process	GO:0045830	positive regulation of isotype switching	Exosc6	IMP		Mouse	PMID:21255825
Biological Process	GO:0006401	RNA catabolic process	EXOSC6	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC6	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC6	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC6	IDA		Human	PMID:20531386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern