Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXOSC8
  • Mouse genes Exosc8
  • Rat genes Exosc8
  • Zfish genes exosc8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Exosc8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	EXOSC8	IPI	UniProtKB:Q96B26	Human	PMID:15231747
Molecular Function	GO:0042802	identical protein binding	EXOSC8	IPI	UniProtKB:Q96B26	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	EXOSC8	IPI	UniProtKB:Q96B26	Human	PMID:32296183
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	EXOSC8	IDA		Human	PMID:16912217
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:12419256
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT5	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y3B2	Human	PMID:15231747
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT5	Human	PMID:20531389
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT5	Human	PMID:21255825
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT5	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y3B2	Human	PMID:25043052
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O14530	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P15336	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P20674	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q01664	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q01804	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q14331	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q15560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q5TAL4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q86VL0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q86Y22	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q86YD7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8WTP8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8WVZ3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9BRA2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9BVJ7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9BVJ7	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y3B2	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P28702-3	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y3B2	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O14512	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O14530	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O75604	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O75928-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O95059	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:O95863	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P09234	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P14678-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P17482	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P40937	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P55040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q01664	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q01804	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q14511-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q14654	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q63ZY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q6P5X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q86YD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8ND83	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8NDC4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8NE01	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q8WUT1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q96BD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q96GV9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q96MY7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9BRA2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9BVJ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9BVN2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9GZV7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9H0A9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NP98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NQT4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9NU39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y272	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y3B2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EXOSC8	IPI	UniProtKB:Q9Y4Z0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Exosc8	IPI	UniProtKB:Q8K4E0	Mouse	MGI:MGI:5436381|PMID:22693585
Cellular Component	GO:0005694	chromosome	EXOSC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	EXOSC8	IDA		Human	PMID:17545563
Cellular Component	GO:0005829	cytosol	EXOSC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	EXOSC8	IDA		Human	PMID:20531386
Cellular Component	GO:0000178	exosome (RNase complex)	EXOSC8	IDA		Human	PMID:20531389
Cellular Component	GO:0001650	fibrillar center	EXOSC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	EXOSC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	EXOSC8	IDA		Human	PMID:20531386
Cellular Component	GO:0005654	nucleoplasm	EXOSC8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EXOSC8	IDA		Human	PMID:17545563
Cellular Component	GO:0005634	nucleus	EXOSC8	IDA		Human	PMID:20531386
Biological Process	GO:0007409	axonogenesis	exosc8	IMP	ZFIN:ZDB-MRPHLNO-140929-2	Zfish	PMID:27193168
Biological Process	GO:0007420	brain development	exosc8	IMP	ZFIN:ZDB-MRPHLNO-140929-2	Zfish	PMID:24989451
Biological Process	GO:0007420	brain development	exosc8	IMP	ZFIN:ZDB-MRPHLNO-140929-1	Zfish	PMID:24989451
Biological Process	GO:0021693	cerebellar Purkinje cell layer structural organization	exosc8	IMP	ZFIN:ZDB-MRPHLNO-140929-2	Zfish	PMID:27193168
Biological Process	GO:0042552	myelination	exosc8	IMP	ZFIN:ZDB-MRPHLNO-140929-1	Zfish	PMID:24989451
Biological Process	GO:0042552	myelination	exosc8	IMP	ZFIN:ZDB-MRPHLNO-140929-2	Zfish	PMID:24989451
Biological Process	GO:0006401	RNA catabolic process	EXOSC8	IDA		Human	PMID:17174896
Biological Process	GO:0006401	RNA catabolic process	EXOSC8	IDA		Human	PMID:20531386
Biological Process	GO:0006396	RNA processing	EXOSC8	IDA		Human	PMID:17174896
Biological Process	GO:0006396	RNA processing	EXOSC8	IDA		Human	PMID:20531386

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern