Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EXTL2
  • Mouse genes Extl2
  • Rat genes Extl2
  • Zfish genes extl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Extl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035248	alpha-1,4-N-acetylgalactosaminyltransferase activity	EXTL2	IDA		Human	PMID:10318803
Molecular Function	GO:0035248	alpha-1,4-N-acetylgalactosaminyltransferase activity	Extl2	IMP		Mouse	MGI:MGI:5882911|PMID:12562774
Molecular Function	GO:0001888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	EXTL2	IDA		Human	PMID:10318803
Molecular Function	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	Extl2	IMP		Mouse	MGI:MGI:5882911|PMID:12562774
Molecular Function	GO:0005539	glycosaminoglycan binding	Extl2	IMP		Mouse	MGI:MGI:5882911|PMID:12562774
Molecular Function	GO:0030145	manganese ion binding	Extl2	IMP		Mouse	MGI:MGI:5882911|PMID:12562774
Molecular Function	GO:0005515	protein binding	EXTL2	IPI	UniProtKB:P14136	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EXTL2	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EXTL2	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Cellular Component	GO:0005829	cytosol	EXTL2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	EXTL2	IDA		Human	PMID:10639137
Cellular Component	GO:0005654	nucleoplasm	EXTL2	IDA		Human	GO_REF:0000052
Biological Process	GO:0006044	N-acetylglucosamine metabolic process	EXTL2	IDA		Human	PMID:10318803
Biological Process	GO:0006044	N-acetylglucosamine metabolic process	Extl2	IMP		Mouse	MGI:MGI:5882911|PMID:12562774
Biological Process	GO:0019276	UDP-N-acetylgalactosamine metabolic process	EXTL2	IDA		Human	PMID:10318803
Biological Process	GO:0019276	UDP-N-acetylgalactosamine metabolic process	Extl2	IMP		Mouse	MGI:MGI:5882911|PMID:12562774

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern