Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EYA4
  • Mouse genes Eya4
  • Rat genes Eya4
  • Zfish genes eya4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eya4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EYA4	IPI	UniProtKB:Q62233	Human	PMID:19606496
Biological Process	GO:0035050	embryonic heart tube development	eya4	IMP		Zfish	PMID:15735644
Biological Process	GO:0007507	heart development	eya4	IGI	ZFIN:ZDB-GENE-010718-1,ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0007507	heart development	eya4	IMP	ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0048839	inner ear development	Eya4	IEP		Rat	PMID:11159937|RGD:1598918
Biological Process	GO:0042472	inner ear morphogenesis	eya4	IMP	ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0042472	inner ear morphogenesis	eya4	IGI	ZFIN:ZDB-GENE-010718-1,ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0042474	middle ear morphogenesis	Eya4	IMP	MGI:MGI:3775095	Mouse	PMID:18219393
Biological Process	GO:0048923	posterior lateral line neuromast hair cell differentiation	eya4	IMP	ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0048923	posterior lateral line neuromast hair cell differentiation	eya4	IGI	ZFIN:ZDB-GENE-010718-1,ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0007605	sensory perception of sound	Eya4	IMP	MGI:MGI:3775095	Mouse	PMID:18219393
Biological Process	GO:0001964	startle response	eya4	IMP	ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547
Biological Process	GO:0001964	startle response	eya4	IGI	ZFIN:ZDB-GENE-010718-1,ZFIN:ZDB-MRPHLNO-081231-4	Zfish	PMID:18799547

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern