Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes F11R
  • Mouse genes F11r
  • Rat genes F11r
  • Zfish genes f11r.1,f11r.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set F11r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	F11R	HDA		Human	PMID:25468996
Molecular Function	GO:0005178	integrin binding	F11R	IPI	UniProtKB:P20701	Human	PMID:11812992
Molecular Function	GO:0005178	integrin binding	F11R	IPI	UniProtKB:P05106	Human	PMID:15344881
Molecular Function	GO:0030165	PDZ domain binding	F11R	IPI	UniProtKB:Q9UDY2	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:P21926	Human	PMID:15344881
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:O43765	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q8TEW0	Human	PMID:17057644
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:O43765	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:P55196	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9Y4G8	Human	PMID:23885123
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:P0DN84	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:P49069	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:P50281	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:P78382	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q5SQN1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q8N5M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q8N661	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q96S97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9BVK8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9NV29	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9P0N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9UHJ9-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9UI14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q92615	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9BV20	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	F11R	IPI	UniProtKB:Q9NP70	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	F11r	IPI	UniProtKB:O08783	Mouse	PMID:11689568
Molecular Function	GO:0005515	protein binding	F11r	IPI	RGD:727803|RGD:1306216	Rat	PMID:16617054|RGD:1582382
Molecular Function	GO:0046982	protein heterodimerization activity	f11r.1	IPI	ZFIN:ZDB-GENE-031204-3	Zfish	PMID:25119047
Molecular Function	GO:0042803	protein homodimerization activity	F11R	IDA		Human	PMID:14749337
Molecular Function	GO:0042803	protein homodimerization activity	F11R	IDA		Human	PMID:15344881
Cellular Component	GO:0005923	bicellular tight junction	F11R	IDA		Human	PMID:23885123
Cellular Component	GO:0005923	bicellular tight junction	F11r	IMP		Mouse	PMID:15494378
Cellular Component	GO:0005911	cell-cell junction	F11r	IDA		Rat	PMID:18506084|RGD:7488940
Cellular Component	GO:0031410	cytoplasmic vesicle	F11r	IDA		Rat	PMID:18506084|RGD:7488940
Cellular Component	GO:0070062	extracellular exosome	F11R	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	F11R	HDA		Human	PMID:20458337
Cellular Component	GO:0005886	plasma membrane	F11R	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005886	plasma membrane	F11R	IDA		Human	PMID:11812992
Cellular Component	GO:0032991	protein-containing complex	F11R	IDA		Human	PMID:15344881
Cellular Component	GO:0036057	slit diaphragm	F11r	IDA		Rat	PMID:19478094|RGD:7488941
Cellular Component	GO:0070160	tight junction	F11R	IMP		Human	PMID:14749337
Biological Process	GO:0031032	actomyosin structure organization	F11R	IMP		Human	PMID:23885123
Biological Process	GO:0007155	cell adhesion	F11r	IDA		Mouse	PMID:15494378
Biological Process	GO:0030154	cell differentiation	F11r	IEP		Rat	PMID:18506084|RGD:7488940
Biological Process	GO:0098609	cell-cell adhesion	F11R	IDA		Human	PMID:14749337
Biological Process	GO:0071260	cellular response to mechanical stimulus	F11R	IDA		Human	PMID:26985018
Biological Process	GO:0030855	epithelial cell differentiation	F11r	IDA		Mouse	PMID:15494378
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	F11R	IGI	UniProtKB:Q9Y3L5	Human	PMID:23885123
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	F11R	IMP		Human	PMID:23885123
Biological Process	GO:0048534	hematopoietic or lymphoid organ development	f11r.1	IMP	ZFIN:ZDB-MRPHLNO-110121-1	Zfish	PMID:25119047
Biological Process	GO:0050892	intestinal absorption	F11R	IMP		Human	PMID:23885123
Biological Process	GO:0050892	intestinal absorption	F11r	IMP		Mouse	MGI:MGI:5613459|PMID:23885123
Biological Process	GO:0007159	leukocyte cell-cell adhesion	F11R	IMP		Human	PMID:11812992
Biological Process	GO:0035683	memory T cell extravasation	F11R	IDA		Human	PMID:11812992
Biological Process	GO:0034260	negative regulation of GTPase activity	F11R	IMP		Human	PMID:23885123
Biological Process	GO:0051497	negative regulation of stress fiber assembly	F11R	IMP		Human	PMID:25753039
Biological Process	GO:0045777	positive regulation of blood pressure	F11r	IDA		Rat	PMID:17420334|RGD:7488939
Biological Process	GO:1903142	positive regulation of establishment of endothelial barrier	F11R	IMP		Human	PMID:26985018
Biological Process	GO:0043547	positive regulation of GTPase activity	F11R	IMP		Human	PMID:23885123
Biological Process	GO:1901731	positive regulation of platelet aggregation	F11R	IDA		Human	PMID:15344881
Biological Process	GO:0035025	positive regulation of Rho protein signal transduction	F11R	IDA		Human	PMID:26985018
Biological Process	GO:0048916	posterior lateral line development	f11r.1	IMP	ZFIN:ZDB-MRPHLNO-110121-1	Zfish	PMID:21144052
Biological Process	GO:1902396	protein localization to bicellular tight junction	F11R	IMP	UniProtKB:O00501|UniProtKB:P18206|UniProtKB:Q07157|UniProtKB:Q13177	Human	PMID:25753039
Biological Process	GO:0072659	protein localization to plasma membrane	F11R	IMP		Human	PMID:23885123
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	F11R	IDA		Human	PMID:15344881
Biological Process	GO:2000249	regulation of actin cytoskeleton reorganization	F11R	IMP		Human	PMID:23885123
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	F11R	IMP		Human	PMID:25753039
Biological Process	GO:0008360	regulation of cell shape	F11R	IDA		Human	PMID:15344881
Biological Process	GO:0001817	regulation of cytokine production	F11r	IMP		Mouse	MGI:MGI:3803039|PMID:18514073
Biological Process	GO:0051493	regulation of cytoskeleton organization	F11R	IMP		Human	PMID:25753039
Biological Process	GO:1902036	regulation of hematopoietic stem cell differentiation	f11r.1	IMP	ZFIN:ZDB-MRPHLNO-110121-1	Zfish	PMID:25119047
Biological Process	GO:0090559	regulation of membrane permeability	F11R	IMP		Human	PMID:23885123
Biological Process	GO:0090559	regulation of membrane permeability	F11r	IMP		Mouse	MGI:MGI:5613459|PMID:23885123
Biological Process	GO:0009314	response to radiation	F11r	IEP		Rat	PMID:20180397|RGD:7488942

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern