Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes F2RL2
  • Mouse genes F2rl2
  • Rat genes F2rl2
  • Zfish genes f2rl2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set F2rl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	F2rl2	IGI	MGI:MGI:88380	Mouse	PMID:26742564
Molecular Function	GO:0005515	protein binding	F2RL2	IPI	UniProtKB:Q1MX18	Human	PMID:16458856
Molecular Function	GO:0005515	protein binding	F2RL2	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0001648	proteinase-activated receptor activity	F2rl2	IGI	MGI:MGI:88380	Mouse	PMID:26742564
Molecular Function	GO:0048018	receptor ligand activity	F2rl2	IDA		Mouse	PMID:26742564
Cellular Component	GO:0016324	apical plasma membrane	F2rl2	IDA		Mouse	PMID:16892058
Cellular Component	GO:0032991	protein-containing complex	F2RL2	IDA		Human	PMID:16458856
Biological Process	GO:0099105	ion channel modulating, G protein-coupled receptor signaling pathway	F2rl2	IDA		Mouse	PMID:26742564
Biological Process	GO:0099105	ion channel modulating, G protein-coupled receptor signaling pathway	F2rl2	IGI	MGI:MGI:88380	Mouse	PMID:26742564
Biological Process	GO:1990806	ligand-gated ion channel signaling pathway	F2rl2	IDA		Mouse	PMID:26742564
Biological Process	GO:1990806	ligand-gated ion channel signaling pathway	F2rl2	IGI	MGI:MGI:88380	Mouse	PMID:26742564
Biological Process	GO:0032024	positive regulation of insulin secretion	F2rl2	IGI	MGI:MGI:88380	Mouse	PMID:26742564
Biological Process	GO:0032024	positive regulation of insulin secretion	F2rl2	IDA		Mouse	PMID:26742564
Biological Process	GO:0009611	response to wounding	F2rl2	IEP		Rat	PMID:12836167|RGD:1299297

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern