Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FABP1
  • Mouse genes Fabp1
  • Rat genes Fabp1
  • Zfish genes fabp1a,fabp1b.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fabp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016209	antioxidant activity	FABP1	IDA		Human	PMID:16175609
Molecular Function	GO:0032052	bile acid binding	Fabp1	IMP		Rat	PMID:12479568|RGD:1626443
Molecular Function	GO:0003682	chromatin binding	Fabp1	IDA		Mouse	PMID:15522233
Molecular Function	GO:0005504	fatty acid binding	Fabp1	IPI	CHEBI:15756	Rat	PMID:10666570|RGD:1582399
Molecular Function	GO:0005504	fatty acid binding	Fabp1	IPI	CHEBI:16196	Rat	PMID:10666570|RGD:1582399
Molecular Function	GO:0005504	fatty acid binding	Fabp1	IDA		Rat	PMID:3478711|RGD:728787
Molecular Function	GO:1901363	heterocyclic compound binding	Fabp1	IDA		Rat	PMID:1939124|RGD:1626448
Molecular Function	GO:1901363	heterocyclic compound binding	Fabp1	IPI	CHEBI:4513|CHEBI:10033	Rat	PMID:1939124|RGD:1626448
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	Fabp1	IMP		Rat	PMID:15035630|RGD:1582395
Molecular Function	GO:0070538	oleic acid binding	Fabp1	IPI	CHEBI:16196	Rat	PMID:1939124|RGD:1626448
Molecular Function	GO:0005543	phospholipid binding	Fabp1	IMP		Rat	PMID:12479568|RGD:1626443
Molecular Function	GO:0005515	protein binding	FABP1	IPI	UniProtKB:P21333-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Fabp1	IPI	UniProtKB:P22449	Rat	PMID:24140341|RGD:8553697
Cellular Component	GO:0045179	apical cortex	Fabp1	IDA		Rat	PMID:10666570|RGD:1582399
Cellular Component	GO:0005737	cytoplasm	Fabp1	IDA		Mouse	PMID:16940177
Cellular Component	GO:0005737	cytoplasm	Fabp1	IDA		Mouse	PMID:17272516
Cellular Component	GO:0005737	cytoplasm	Fabp1	IDA		Rat	PMID:10666570|RGD:1582399
Cellular Component	GO:0005829	cytosol	FABP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Fabp1	IDA		Rat	PMID:16262600|RGD:1626442
Cellular Component	GO:0070062	extracellular exosome	FABP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FABP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	FABP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Fabp1	IDA		Mouse	PMID:17272516
Cellular Component	GO:0005634	nucleus	Fabp1	IDA		Rat	PMID:16262600|RGD:1626442
Cellular Component	GO:0005782	peroxisomal matrix	Fabp1	IDA		Rat	PMID:16262600|RGD:1626442
Cellular Component	GO:0032991	protein-containing complex	Fabp1	IDA		Rat	PMID:22303004|RGD:10413913
Biological Process	GO:0070301	cellular response to hydrogen peroxide	FABP1	IDA		Human	PMID:16175609
Biological Process	GO:0071456	cellular response to hypoxia	FABP1	IDA		Human	PMID:16175609
Biological Process	GO:0050892	intestinal absorption	Fabp1	IDA		Rat	PMID:10666570|RGD:1582399
Biological Process	GO:0015909	long-chain fatty acid transport	Fabp1	IMP		Rat	PMID:15035630|RGD:1582395
Biological Process	GO:0043066	negative regulation of apoptotic process	FABP1	IDA		Human	PMID:16175609
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	FABP1	IDA		Human	PMID:16175609
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Fabp1	IDA		Rat	PMID:16262600|RGD:1626442
Biological Process	GO:0051345	positive regulation of hydrolase activity	Fabp1	IDA		Rat	PMID:16262600|RGD:1626442
Biological Process	GO:0033993	response to lipid	fabp1b.1	IDA		Zfish	PMID:26658423

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern