Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FABP4
  • Mouse genes Fabp4
  • Rat genes Fabp4
  • Zfish genes fabp4a,fabp4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fabp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051427	hormone receptor binding	Fabp4	IPI	UniProtKB:P37238	Mouse	MGI:MGI:6158968|PMID:12077340
Molecular Function	GO:0036041	long-chain fatty acid binding	Fabp4	IDA		Mouse	MGI:MGI:6158968|PMID:12077340
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	Fabp4	IDA		Mouse	MGI:MGI:6158968|PMID:12077340
Molecular Function	GO:0005515	protein binding	Fabp4	IPI	RGD:3010	Rat	PMID:10318917|RGD:68775
Cellular Component	GO:0005737	cytoplasm	Fabp4	IDA		Mouse	MGI:MGI:6158872|PMID:17516629
Cellular Component	GO:0005737	cytoplasm	Fabp4	IDA		Mouse	MGI:MGI:6158757|PMID:17761196
Cellular Component	GO:0005829	cytosol	Fabp4	IDA		Rat	PMID:9059981|RGD:1625411
Cellular Component	GO:0070062	extracellular exosome	FABP4	HDA		Human	PMID:23533145
Cellular Component	GO:0005634	nucleus	Fabp4	IDA		Mouse	MGI:MGI:6158872|PMID:17516629
Cellular Component	GO:0005634	nucleus	Fabp4	IDA		Mouse	MGI:MGI:6158757|PMID:17761196
Biological Process	GO:0050873	brown fat cell differentiation	Fabp4	IDA		Mouse	PMID:18492766
Biological Process	GO:0071285	cellular response to lithium ion	Fabp4	IDA		Mouse	PMID:15673614
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Fabp4	IDA		Mouse	PMID:1618860
Biological Process	GO:0042632	cholesterol homeostasis	Fabp4	IMP	MGI:MGI:2148887	Mouse	PMID:15684432
Biological Process	GO:0001816	cytokine production	Fabp4	IMP	MGI:MGI:2148887	Mouse	PMID:15684432
Biological Process	GO:0001654	eye development	fabp4a	IMP	ZFIN:ZDB-MRPHLNO-170124-3	Zfish	PMID:27834346
Biological Process	GO:0001654	eye development	fabp4a	IMP	ZFIN:ZDB-CRISPR-170405-1	Zfish	PMID:27834346
Biological Process	GO:0006631	fatty acid metabolic process	Fabp4	IDA		Rat	PMID:9425108|RGD:68776
Biological Process	GO:0015909	long-chain fatty acid transport	Fabp4	IDA		Mouse	MGI:MGI:6158968|PMID:12077340
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Fabp4	IMP	MGI:MGI:2148887	Mouse	PMID:15684432
Biological Process	GO:0006469	negative regulation of protein kinase activity	Fabp4	IMP	MGI:MGI:2148887	Mouse	PMID:15684432
Biological Process	GO:0008284	positive regulation of cell population proliferation	Fabp4	IMP		Rat	PMID:9425108|RGD:68776
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Fabp4	IGI	UniProtKB:Q05816	Mouse	MGI:MGI:5613438|PMID:24603714
Biological Process	GO:0050729	positive regulation of inflammatory response	Fabp4	IMP	MGI:MGI:2148887	Mouse	PMID:15684432
Biological Process	GO:0009617	response to bacterium	Fabp4	IEP		Mouse	PMID:23012479
Biological Process	GO:0051384	response to glucocorticoid	Fabp4	IEP		Rat	PMID:12704799|RGD:1625409
Biological Process	GO:0009629	response to gravity	Fabp4	IEP		Rat	PMID:14638460|RGD:151361116
Biological Process	GO:0034694	response to prostaglandin	fabp4b	IDA		Zfish	PMID:18752667
Biological Process	GO:0033552	response to vitamin B3	fabp4b	IDA		Zfish	PMID:18752667
Biological Process	GO:0009410	response to xenobiotic stimulus	Fabp4	IEP		Rat	PMID:17391165|RGD:1625407
Biological Process	GO:0050872	white fat cell differentiation	Fabp4	IDA		Mouse	PMID:18492766

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern