Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FADS1
  • Mouse genes Fads1
  • Rat genes Fads1
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fads1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0062076	acyl-CoA delta5-desaturase activity	FADS1	IDA		Human	PMID:10769175
Molecular Function	GO:0062076	acyl-CoA delta5-desaturase activity	Fads1	IMP		Mouse	MGI:MGI:5431280|PMID:22534642
Molecular Function	GO:0062076	acyl-CoA delta5-desaturase activity	Fads1	IDA		Rat	PMID:24070791|RGD:39458027
Molecular Function	GO:0016213	linoleoyl-CoA desaturase activity	FADS1	IDA		Human	PMID:10601301
Molecular Function	GO:0016491	oxidoreductase activity	FADS1	IDA		Human	PMID:10601301
Molecular Function	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	Fads1	IDA		Rat	PMID:11414679|RGD:632758
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	Fads1	IDA		Rat	PMID:8177224|RGD:1625419
Cellular Component	GO:0016020	membrane	FADS1	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	Fads1	IDA		Rat	PMID:7770068|RGD:1625422
Biological Process	GO:0007568	aging	Fads1	IEP		Rat	PMID:8487621|RGD:1625420
Biological Process	GO:0019369	arachidonic acid metabolic process	Fads1	IMP		Rat	PMID:11414679|RGD:632758
Biological Process	GO:0009267	cellular response to starvation	FADS1	IDA		Human	PMID:10601301
Biological Process	GO:0042759	long-chain fatty acid biosynthetic process	FADS1	IDA		Human	PMID:10601301
Biological Process	GO:0032868	response to insulin	Fads1	IEP		Rat	PMID:16099631|RGD:1625413
Biological Process	GO:0035900	response to isolation stress	Fads1	IEP		Rat	PMID:8115350|RGD:1625418
Biological Process	GO:0007584	response to nutrient	Fads1	IEP		Rat	PMID:16333142|RGD:1625417
Biological Process	GO:0014070	response to organic cyclic compound	Fads1	IEP		Rat	PMID:16099631|RGD:1625413
Biological Process	GO:0010033	response to organic substance	Fads1	IEP		Rat	PMID:11841597|RGD:1625416
Biological Process	GO:0009744	response to sucrose	Fads1	IEP		Rat	PMID:14506836|RGD:1625414
Biological Process	GO:0033189	response to vitamin A	Fads1	IEP		Rat	PMID:11414679|RGD:632758
Biological Process	GO:0006636	unsaturated fatty acid biosynthetic process	FADS1	IDA		Human	PMID:10601301
Biological Process	GO:0006636	unsaturated fatty acid biosynthetic process	Fads1	IDA		Rat	PMID:11414679|RGD:632758

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern