Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAM107A
  • Mouse genes Fam107a
  • Rat genes Fam107a
  • Zfish genes si:ch211-236d3.4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fam107a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FAM107A	IPI	UniProtKB:P78559	Human	PMID:20543869
Molecular Function	GO:0005515	protein binding	FAM107A	IPI	UniProtKB:P60709	Human	PMID:28604741
Molecular Function	GO:0005515	protein binding	FAM107A	IPI	UniProtKB:Q8N668	Human	PMID:28604741
Molecular Function	GO:0005515	protein binding	Fam107a	IPI	UniProtKB:P60709|UniProtKB:Q06830	Mouse	MGI:MGI:6162291|PMID:21969592
Cellular Component	GO:0015629	actin cytoskeleton	FAM107A	IDA		Human	PMID:28604741
Cellular Component	GO:0015629	actin cytoskeleton	Fam107a	IDA		Mouse	MGI:MGI:6162291|PMID:21969592
Cellular Component	GO:0005737	cytoplasm	FAM107A	IDA		Human	PMID:28604741
Cellular Component	GO:0005925	focal adhesion	FAM107A	IDA		Human	PMID:20543869
Cellular Component	GO:0043005	neuron projection	Fam107a	IDA		Mouse	MGI:MGI:6162291|PMID:21969592
Cellular Component	GO:0043005	neuron projection	Fam107a	IDA		Mouse	PMID:20298674
Cellular Component	GO:0043005	neuron projection	Fam107a	IDA		Rat	PMID:20298674|RGD:8554505
Cellular Component	GO:0043005	neuron projection	Fam107a	IDA		Rat	PMID:21969592|RGD:13673873
Cellular Component	GO:0016607	nuclear speck	FAM107A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FAM107A	IDA		Human	PMID:10564580
Cellular Component	GO:0005634	nucleus	FAM107A	IDA		Human	PMID:20543869
Cellular Component	GO:0005634	nucleus	FAM107A	IDA		Human	PMID:28604741
Cellular Component	GO:0032587	ruffle membrane	FAM107A	IDA		Human	PMID:20543869
Cellular Component	GO:0001725	stress fiber	FAM107A	IDA		Human	PMID:20543869
Cellular Component	GO:0045202	synapse	Fam107a	IDA		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0051017	actin filament bundle assembly	Fam107a	IMP		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0030041	actin filament polymerization	Fam107a	IMP		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0071385	cellular response to glucocorticoid stimulus	Fam107a	IMP		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0031669	cellular response to nutrient levels	Fam107a	IMP		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0050890	cognition	Fam107a	IMP		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	FAM107A	IMP		Human	PMID:20543869
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	FAM107A	IMP		Human	PMID:28604741
Biological Process	GO:1900272	negative regulation of long-term synaptic potentiation	Fam107a	IMP		Mouse	MGI:MGI:6162291|PMID:21969592
Biological Process	GO:0030335	positive regulation of cell migration	FAM107A	IMP		Human	PMID:20543869
Biological Process	GO:0031398	positive regulation of protein ubiquitination	FAM107A	IMP		Human	PMID:28604741
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	FAM107A	IMP		Human	PMID:20543869
Biological Process	GO:0001558	regulation of cell growth	FAM107A	IDA		Human	PMID:10564580
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	FAM107A	IMP		Human	PMID:20543869
Biological Process	GO:0031647	regulation of protein stability	FAM107A	IMP		Human	PMID:28604741

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern