Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAM89B
  • Mouse genes Fam89b
  • Rat genes Fam89b
  • Zfish genes fam89b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fam89b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Fam89b	IPI	UniProtKB:P12755	Mouse	MGI:MGI:5486566|PMID:12646588
Molecular Function	GO:0005515	protein binding	Fam89b	IPI	UniProtKB:P53668|UniProtKB:Q3UU96|UniProtKB:Q7TT50	Mouse	MGI:MGI:5908532|PMID:25107909
Molecular Function	GO:0005515	protein binding	Fam89b	IPI	UniProtKB:O54874|UniProtKB:Q7TT49	Rat	PMID:25107909|RGD:13210541
Molecular Function	GO:0001222	transcription corepressor binding	Fam89b	IDA		Mouse	MGI:MGI:5486566|PMID:12646588
Cellular Component	GO:0005737	cytoplasm	Fam89b	IDA		Mouse	MGI:MGI:5486566|PMID:12646588
Cellular Component	GO:0030027	lamellipodium	Fam89b	IDA		Mouse	MGI:MGI:5908532|PMID:25107909
Biological Process	GO:0030010	establishment of cell polarity	Fam89b	IMP		Mouse	MGI:MGI:5908532|PMID:25107909
Biological Process	GO:0060392	negative regulation of SMAD protein signal transduction	Fam89b	IDA		Mouse	MGI:MGI:5486566|PMID:12646588
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Fam89b	IDA		Mouse	MGI:MGI:5486566|PMID:12646588
Biological Process	GO:0030335	positive regulation of cell migration	Fam89b	IMP		Mouse	MGI:MGI:5908532|PMID:25107909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern