Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FANCA
  • Mouse genes Fanca
  • Rat genes Fanca
  • Zfish genes fanca
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fanca

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:10627486
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:10652215
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:11063725
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q9NPI8	Human	PMID:11063725
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:P51532	Human	PMID:11726552
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q92889	Human	PMID:12571280
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:12649160
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q9NPI8	Human	PMID:12649160
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:17289582
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:17396147
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q0VG06	Human	PMID:17396147
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:P62993	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q6NZ36-1	Human	PMID:22266823
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q6NZ36	Human	PMID:22343915
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:Q6NZ36	Human	PMID:22705371
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FANCA	IPI	UniProtKB:O15287	Human	PMID:32814053
Cellular Component	GO:0000785	chromatin	FANCA	IDA		Human	PMID:22343915
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCA	IDA		Human	PMID:20347428
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCA	IDA		Human	PMID:22266823
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCA	IDA		Human	PMID:22343915
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCA	IDA		Human	PMID:22705371
Cellular Component	GO:0005654	nucleoplasm	FANCA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FANCA	IDA		Human	PMID:11726552
Biological Process	GO:0008585	female gonad development	Fanca	IMP	MGI:MGI:2674095	Mouse	PMID:12913077
Biological Process	GO:0008584	male gonad development	Fanca	IMP	MGI:MGI:2674095	Mouse	PMID:12913077
Biological Process	GO:0007140	male meiotic nuclear division	Fanca	IMP	MGI:MGI:2674095	Mouse	PMID:12913077
Biological Process	GO:0006513	protein monoubiquitination	FANCA	IDA		Human	PMID:24910428
Biological Process	GO:2000348	regulation of CD40 signaling pathway	Fanca	IMP	MGI:MGI:2674094	Mouse	PMID:24501220
Biological Process	GO:0051090	regulation of DNA-binding transcription factor activity	Fanca	IMP	MGI:MGI:2674094	Mouse	PMID:24501220
Biological Process	GO:1905936	regulation of germ cell proliferation	Fanca	IMP	MGI:MGI:2674095	Mouse	PMID:12913077
Biological Process	GO:0050727	regulation of inflammatory response	Fanca	IMP	MGI:MGI:2674094	Mouse	PMID:24501220
Biological Process	GO:0045589	regulation of regulatory T cell differentiation	Fanca	IMP	MGI:MGI:2674094	Mouse	PMID:24501220

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern