Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FANCL
  • Mouse genes Fancl
  • Rat genes Fancl
  • Zfish genes fancl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fancl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9NPD8	Human	PMID:24389026
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:P28799	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q8IUH3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q8IYA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q8NF50-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9BRK4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9NRA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9NX63	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9UFD9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9UKT9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9Y2D8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:A2RRN7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:A6NJ78-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:O43307	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:O95865	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:P09016	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:P15976-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:P49720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q02363	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q3KP44	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q3LI70	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q52LG2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q5BKX5-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q5T4B2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q5W5X9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q6BCY4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q6NVU6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q6NX45	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q6PF18	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q8IUC1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q8IXS7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q96H20	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9BQD7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9BSH5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9BVG8-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9GZU7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9NX63	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9NZL3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9P0T4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9UDW3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FANCL	IPI	UniProtKB:Q9Y3C5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fancl	IPI	UniProtKB:Q8VDW4	Mouse	MGI:MGI:5298330|PMID:21229326
Molecular Function	GO:0005515	protein binding	Fancl	IPI	PR:Q80WJ1	Mouse	PMID:23451117
Molecular Function	GO:0005515	protein binding	Fancl	IPI	PR:Q80WJ1	Mouse	PMID:12574169
Molecular Function	GO:0061630	ubiquitin protein ligase activity	FANCL	IDA		Human	PMID:19589784
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Fancl	IDA		Mouse	PMID:21229326
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FANCL	IPI	UniProtKB:Q9NPD8	Human	PMID:16916645
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FANCL	IPI	UniProtKB:Q9NPD8	Human	PMID:17938197
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FANCL	IPI	UniProtKB:Q96B02	Human	PMID:19111657
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FANCL	IPI	UniProtKB:Q9NPD8	Human	PMID:19111657
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	FANCL	IDA		Human	PMID:16916645
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	FANCL	IDA		Human	PMID:19111657
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	Fancl	IDA		Mouse	MGI:MGI:5298330|PMID:21229326
Cellular Component	GO:0000785	chromatin	FANCL	IDA		Human	PMID:22343915
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCL	IDA		Human	PMID:20347428
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCL	IDA		Human	PMID:22343915
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	FANCL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	FANCL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005635	nuclear envelope	Fancl	IPI	PR:Q80WJ1	Mouse	PMID:12574169
Cellular Component	GO:0005634	nucleus	Fancl	IPI	UniProtKB:Q80WI9	Mouse	PMID:12574169
Biological Process	GO:0006974	DNA damage response	FANCL	IMP		Human	PMID:16916645
Biological Process	GO:0006281	DNA repair	FANCL	IMP		Human	PMID:16916645
Biological Process	GO:0007276	gamete generation	Fancl	IMP	MGI:MGI:1861640	Mouse	PMID:12417526
Biological Process	GO:0048599	oocyte development	fancl	IMP	ZFIN:ZDB-GENO-100810-2	Zfish	PMID:20661450
Biological Process	GO:0006513	protein monoubiquitination	FANCL	IDA		Human	PMID:16916645
Biological Process	GO:0006513	protein monoubiquitination	FANCL	IDA		Human	PMID:24389026
Biological Process	GO:0006513	protein monoubiquitination	FANCL	IDA		Human	PMID:24910428
Biological Process	GO:0042127	regulation of cell population proliferation	Fancl	IMP	MGI:MGI:1861640	Mouse	PMID:12417526

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern