Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAT4
  • Mouse genes Fat4
  • Rat genes Fat4
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fat4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FAT4	IPI	UniProtKB:Q9H2K2	Human	PMID:22153077
Molecular Function	GO:0005515	protein binding	Fat4	IPI	PR:Q8VBX6	Mouse	PMID:19506035
Cellular Component	GO:0045177	apical part of cell	Fat4	IDA		Mouse	PMID:19506035
Cellular Component	GO:0070062	extracellular exosome	FAT4	HDA		Human	PMID:23533145
Biological Process	GO:0001658	branching involved in ureteric bud morphogenesis	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:21303848
Biological Process	GO:0021987	cerebral cortex development	Fat4	IMP		Mouse	MGI:MGI:4821246|PMID:19506035
Biological Process	GO:0072137	condensed mesenchymal cell proliferation	Fat4	IGI	MGI:MGI:102778	Mouse	PMID:26116661
Biological Process	GO:0072137	condensed mesenchymal cell proliferation	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:26116661
Biological Process	GO:0048565	digestive tract development	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:21303848
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:26116661
Biological Process	GO:0003007	heart morphogenesis	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:21303848
Biological Process	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	Fat4	IDA		Mouse	MGI:MGI:4821246|PMID:19506035
Biological Process	GO:0035329	hippo signaling	Fat4	IMP		Mouse	MGI:MGI:5544531|PMID:24056717
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:21303848
Biological Process	GO:0001822	kidney development	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:21303848
Biological Process	GO:0072006	nephron development	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:26116661
Biological Process	GO:0022008	neurogenesis	Fat4	IMP		Mouse	MGI:MGI:5544531|PMID:24056717
Biological Process	GO:0007219	Notch signaling pathway	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:26116661
Biological Process	GO:0043931	ossification involved in bone maturation	Fat4	IMP	MGI:MGI:3846573	Mouse	PMID:21303848
Biological Process	GO:0007009	plasma membrane organization	Fat4	IMP		Mouse	PMID:19506035
Biological Process	GO:0072307	regulation of metanephric nephron tubule epithelial cell differentiation	Fat4	IMP		Mouse	PMID:23974041

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern