Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBH1
  • Mouse genes Fbh1
  • Rat genes Fbh1
  • Zfish genes fbxo18
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043138	3'-5' DNA helicase activity	FBH1	IDA		Human	PMID:11956208
Molecular Function	GO:0043138	3'-5' DNA helicase activity	FBH1	IDA		Human	PMID:23393192
Molecular Function	GO:0003678	DNA helicase activity	FBH1	IDA		Human	PMID:19736316
Molecular Function	GO:0003678	DNA helicase activity	FBH1	IMP		Human	PMID:23361013
Molecular Function	GO:0015616	DNA translocase activity	FBH1	IDA		Human	PMID:24108124
Molecular Function	GO:0003690	double-stranded DNA binding	FBH1	IDA		Human	PMID:23393192
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:Q06609	Human	PMID:23393192
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:P12931	Human	PMID:23954233
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:Q06609	Human	PMID:25585578
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:O00213-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FBH1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Fbh1	IPI	UniProtKB:Q06609	Mouse	MGI:MGI:5566975|PMID:24108124
Molecular Function	GO:0003697	single-stranded DNA binding	FBH1	IDA		Human	PMID:19736316
Molecular Function	GO:0003697	single-stranded DNA binding	FBH1	IDA		Human	PMID:23393192
Cellular Component	GO:0000785	chromatin	FBH1	IDA		Human	PMID:23319600
Cellular Component	GO:0005634	nucleus	FBH1	IDA		Human	PMID:19736316
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBH1	IDA		Human	PMID:11956208
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBH1	IDA		Human	PMID:19736316
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBH1	IDA		Human	PMID:25585578
Biological Process	GO:0008219	cell death	FBH1	IDA		Human	PMID:23319600
Biological Process	GO:0008219	cell death	FBH1	IMP		Human	PMID:23361013
Biological Process	GO:0006308	DNA catabolic process	FBH1	IMP		Human	PMID:23361013
Biological Process	GO:0006974	DNA damage response	FBH1	IDA		Human	PMID:19736316
Biological Process	GO:0006974	DNA damage response	FBH1	IDA		Human	PMID:23319600
Biological Process	GO:0006974	DNA damage response	FBH1	IDA		Human	PMID:23361013
Biological Process	GO:0006974	DNA damage response	FBH1	IDA		Human	PMID:25585578
Biological Process	GO:0035562	negative regulation of chromatin binding	Fbh1	IMP		Mouse	PMID:24108124
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	FBH1	IDA		Human	PMID:19736316
Biological Process	GO:2000042	negative regulation of double-strand break repair via homologous recombination	Fbh1	IMP		Mouse	MGI:MGI:5566975|PMID:24108124
Biological Process	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	FBH1	IMP		Human	PMID:23361013
Biological Process	GO:0001934	positive regulation of protein phosphorylation	FBH1	IMP		Human	PMID:23361013
Biological Process	GO:0016567	protein ubiquitination	FBH1	IDA		Human	PMID:25585578
Biological Process	GO:0031297	replication fork processing	FBH1	IDA		Human	PMID:25585578
Biological Process	GO:0031297	replication fork processing	Fbh1	IMP		Mouse	MGI:MGI:5566975|PMID:24108124
Biological Process	GO:0072429	response to intra-S DNA damage checkpoint signaling	FBH1	IMP		Human	PMID:23361013
Biological Process	GO:0072429	response to intra-S DNA damage checkpoint signaling	Fbh1	IMP		Mouse	PMID:23361013

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern