Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBP1
  • Mouse genes Fbp1
  • Rat genes Fbp1
  • Zfish genes fbp1a,fbp1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016208	AMP binding	FBP1	IDA		Human	PMID:10222032
Molecular Function	GO:0016208	AMP binding	FBP1	IDA		Human	PMID:18650089
Molecular Function	GO:0016208	AMP binding	FBP1	IDA		Human	PMID:8387495
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	FBP1	IDA		Human	PMID:16442285
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	FBP1	IDA		Human	PMID:18650089
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	FBP1	IMP		Human	PMID:19259699
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	FBP1	IMP		Human	PMID:20096900
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	FBP1	IMP		Human	PMID:7558035
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	FBP1	IDA		Human	PMID:8387495
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	Fbp1	IMP		Mouse	PMID:30150719
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	Fbp1	IDA		Rat	PMID:11440903|RGD:2302970
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	Fbp1	IDA		Rat	PMID:14342527|RGD:2301230
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	Fbp1	IDA		Rat	PMID:1834654|RGD:1599371
Molecular Function	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity	Fbp1	IDA		Rat	PMID:4353083|RGD:2302851
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:16169070
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:16189514
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:16442285
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:18650089
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:21516116
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:25502805
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:25910212
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	FBP1	IPI	UniProtKB:P09467	Human	PMID:32296183
Molecular Function	GO:0046872	metal ion binding	FBP1	IMP		Human	PMID:8387495
Molecular Function	GO:0048029	monosaccharide binding	Fbp1	IDA		Rat	PMID:14342527|RGD:2301230
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:P16118	Human	PMID:10222032
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:P51116	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O00499	Human	PMID:16275660
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:Q16665	Human	PMID:25043030
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:Q99814	Human	PMID:25043030
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O00757	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O00757	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O00757	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O00757	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:P51116	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O00757	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FBP1	IPI	UniProtKB:O60825	Human	PMID:8387495
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	FBP1	IMP		Human	PMID:25043030
Cellular Component	GO:0005737	cytoplasm	FBP1	IDA		Human	PMID:20096900
Cellular Component	GO:0005829	cytosol	Fbp1	IDA		Rat	PMID:1834654|RGD:1599371
Cellular Component	GO:0070062	extracellular exosome	FBP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	FBP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Fbp1	IDA		Rat	PMID:28101822|RGD:152995487
Cellular Component	GO:0005634	nucleus	FBP1	IMP		Human	PMID:25043030
Biological Process	GO:0005975	carbohydrate metabolic process	Fbp1	IDA		Rat	PMID:1834654|RGD:1599371
Biological Process	GO:0071475	cellular hyperosmotic salinity response	Fbp1	IEP		Rat	PMID:9530152|RGD:151665787
Biological Process	GO:0071477	cellular hypotonic salinity response	Fbp1	IEP		Rat	PMID:9530152|RGD:151665787
Biological Process	GO:0071320	cellular response to cAMP	Fbp1	IEP		Rat	PMID:9530152|RGD:151665787
Biological Process	GO:0071391	cellular response to estrogen stimulus	fbp1b	IDA		Zfish	PMID:18618001
Biological Process	GO:0032869	cellular response to insulin stimulus	Fbp1	IEP		Rat	PMID:2847161|RGD:1298915
Biological Process	GO:0032869	cellular response to insulin stimulus	Fbp1	IEP		Rat	PMID:9530152|RGD:151665787
Biological Process	GO:0071286	cellular response to magnesium ion	FBP1	IDA		Human	PMID:10222032
Biological Process	GO:1904628	cellular response to phorbol 13-acetate 12-myristate	Fbp1	IEP		Rat	PMID:9530152|RGD:151665787
Biological Process	GO:0097403	cellular response to raffinose	Fbp1	IEP		Rat	PMID:9530152|RGD:151665787
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	FBP1	IDA		Human	PMID:16442285
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	FBP1	IDA		Human	PMID:18650089
Biological Process	GO:0016311	dephosphorylation	FBP1	IDA		Human	PMID:18650089
Biological Process	GO:0016311	dephosphorylation	FBP1	IMP		Human	PMID:7558035
Biological Process	GO:0016311	dephosphorylation	FBP1	IDA		Human	PMID:8387495
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	FBP1	IDA		Human	PMID:16442285
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	FBP1	IDA		Human	PMID:8387495
Biological Process	GO:0006002	fructose 6-phosphate metabolic process	Fbp1	IDA		Rat	PMID:14342527|RGD:2301230
Biological Process	GO:0006094	gluconeogenesis	FBP1	IMP		Human	PMID:19259699
Biological Process	GO:0006094	gluconeogenesis	FBP1	IMP		Human	PMID:20096900
Biological Process	GO:0006094	gluconeogenesis	Fbp1	IMP		Mouse	PMID:30150719
Biological Process	GO:0006094	gluconeogenesis	Fbp1	IDA		Rat	PMID:11440903|RGD:2302970
Biological Process	GO:0006094	gluconeogenesis	Fbp1	IDA		Rat	PMID:4353083|RGD:2302851
Biological Process	GO:0030308	negative regulation of cell growth	FBP1	IDA		Human	PMID:19881551
Biological Process	GO:0045820	negative regulation of glycolytic process	FBP1	IDA		Human	PMID:19881551
Biological Process	GO:0045820	negative regulation of glycolytic process	FBP1	IMP		Human	PMID:25043030
Biological Process	GO:0046580	negative regulation of Ras protein signal transduction	FBP1	IDA		Human	PMID:19881551
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	FBP1	IMP		Human	PMID:25043030
Biological Process	GO:0006111	regulation of gluconeogenesis	FBP1	IMP		Human	PMID:7558035
Biological Process	GO:0009409	response to cold	Fbp1	IEP		Rat	PMID:29504286|RGD:152995491
Biological Process	GO:1901558	response to metformin	Fbp1	IEP		Rat	PMID:23307605|RGD:152177519
Biological Process	GO:1901558	response to metformin	Fbp1	IEP		Rat	PMID:28101822|RGD:152995487
Biological Process	GO:0031667	response to nutrient levels	Fbp1	IEP		Rat	PMID:23307605|RGD:152177519

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern