Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXL14
  • Mouse genes Fbxl14
  • Rat genes
  • Zfish genes fbxl14a,fbxl14b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxl14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXL14	IPI	UniProtKB:O95863	Human	PMID:19955572
Molecular Function	GO:0005515	protein binding	FBXL14	IPI	UniProtKB:O95863	Human	PMID:25203322
Molecular Function	GO:0005515	protein binding	FBXL14	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXL14	IPI	UniProtKB:P63208	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FBXL14	IPI	UniProtKB:P63208	Human	PMID:32296183
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	FBXL14	IDA		Human	PMID:19955572
Cellular Component	GO:0005737	cytoplasm	FBXL14	IDA		Human	PMID:19955572
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	fbxl14b	IPI	UniProtKB:Q9W5E1	Zfish	PMID:11976951
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	fbxl14a	IPI	UniProtKB:Q9W5E1	Zfish	PMID:11976951
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	FBXL14	IDA		Human	PMID:19955572

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern